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SUB-UNIFIED VACCINE AGAINST CIRCOVIRUS OF PIGS TYPE 2 (PCV2)

机译:抗2型猪圆环病毒(PCV2)的亚单位疫苗

摘要

The present invention relates to an immunogenic composition against swine circovirus type 2 (PCV2) containing an antigenic peptide. The antigenic peptide is an open-reading arginine-enriched peptide 2 (ORF2) from PCV2 and / or a recombinant chimeric protein, which is a construct from an arginine-enriched peptide from ORF2 from PCV2, PE peptide and the KDEL signal peptide. The amount of arginine of the arginine-rich peptide from ORF2 from PCV2 is no more than half the amount of arginine enriched in the arginine domain at the N-terminus of ORF2 from PCV2.
机译:本发明涉及包含抗原性肽的抗2型猪圆环病毒(PCV2)的免疫原性组合物。抗原性肽是来自PCV2的开放阅读精氨酸富集的肽2(ORF2)和/或重组嵌合蛋白,其是来自来自PCV2的ORF2富精氨酸的肽,PE肽和KDEL信号肽的构建体。来自PCV2的来自ORF2的富含精氨酸的肽的精氨酸的量不超过来自PCV2的ORF2的N末端在精氨酸域中富集的精氨酸的量的一半。

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