As the modulator of the reactions of interleucine 12 (IL-12), interleucine 23 (IL-23) and / or interferon alpha (IFN (α)), the heterocyclic compounds substituted by Sulfanilamide

摘要

The invention refers to a compound containing the following formula: or a stereoisomer or salt acceptable to the same agent, wherein R1, R2, R3, R4 and R5, as defined herein, can be used for IL-12, IL-23 and / or ifnalfa modules operating in tyk-2 to inhibit transformation in senaar state.