首页> 外国专利> METHOD FOR MANUFACTURING CARDIAC MUSCLE TISSUE CHIP USED IN SCREENING OF DRUG CANDIDATE COMPOUND

METHOD FOR MANUFACTURING CARDIAC MUSCLE TISSUE CHIP USED IN SCREENING OF DRUG CANDIDATE COMPOUND

机译:制造用于候选毒品药筛查的心脏肌肉组织芯片的方法

摘要

Provided is a method or the like for manufacturing a cardiac muscle tissue chip in which a 3D structure of cardiac muscle is formed and that can be used in screening of drugs. The present invention pertains to a method for manufacturing a cardiac muscle tissue chip used in screening of drugs, the method for manufacturing a cardiac muscle tissue chip comprising disposing, on a substrate, test cells in which the surface of the cells is coated with a film containing an extracellular matrix component, and forming a cardiac muscle 3D tissue construct on the substrate by repeatedly disposing the test cells, the cells comprising cardiac muscle cells derived from artificial multipotent stem cells.
机译:提供了一种用于制造心肌组织芯片的方法等,在该方法中,形成了心肌的3D结构并且可以用于药物的筛选。本发明涉及一种用于筛选药物的心肌组织芯片的制造方法,该制造心肌组织芯片的方法包括在基板上放置测试细胞,其中所述细胞的表面涂有膜。包含细胞外基质成分,并通过重复放置测试细胞在基底上形成心肌3D组织构造,该细胞包含源自人工多能干细胞的心肌细胞。

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