A method and camera assembly for use in a machine vision system, the assembly comprising a support structure forming a mounting flange that is configured for coupling with any of a plurality of exchangeable electrically controllable adjustable focal length lens assemblies, a two dimensional image sensor supported by the support structure and forming a sensor plane spaced from the mounting flange by a flange focal distance and a processor programmed with a flange focal distance error and to use the flange focal distance error to generate lens control signals to compensate for the flange focal distance error when a lens is mounted to the mounting flange.
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