首页> 外国专利> 3-HYDROXYALDEHYDE AND/OR 3-HYDROXYPROPIONIC ACID-PRODUCING RECOMBINANT MICROORGANISM AND METHOD OF PRODUCING 3-HYDROXYALDEHYDE AND/OR 3-HYDROXYPROPIONIC ACID USING THE SAME

3-HYDROXYALDEHYDE AND/OR 3-HYDROXYPROPIONIC ACID-PRODUCING RECOMBINANT MICROORGANISM AND METHOD OF PRODUCING 3-HYDROXYALDEHYDE AND/OR 3-HYDROXYPROPIONIC ACID USING THE SAME

机译:产生3-羟基丙醛和/或3-羟基丙酸的重组微生物及使用相同的方法生产3-羟基乙醛和/或3-羟基丙酸的方法

摘要

The present invention is 3-hydroxy-propionaldehyde (3-Hydroxypropionaldehyde) and / or 3-hydroxypropionic acid (3-Hydroxypropionic acid; 3-HP) in the production of recombinant microorganisms and 3-HPA and / or 3-HP using the same It relates to a production method. Nouri is the recombinant microorganism according to the invention Rosedale Calabria you borane switch (Roseburia inulinivorans) there contains the gene coding for the Hydra hydratase (glycerol dehydratase) having glycerol-derived, Clostridium butyric rikum (Clostridium butyricum) the known in the vitamin B 12-dependent glycerol-derived to 3-HPA and 3-HP production than the recombinant microorganism containing the gene coding for the Hydra hydratase shows a significantly better activity. Accordingly, the present invention has an effect that can be economically mass obtained in the 3-HPA and 3-HP from the culture, and culturing the microorganism. ;
机译:本发明是 3-羟基丙醛(3-羟基丙醛)和/或3-羟基丙酸(3-羟基丙酸; 3-HP),用于生产重组微生物和3-HPA和/或使用其的3-HP。涉及生产方法。诺里(Nouri)是根据本发明的重组微生物罗斯代·卡拉布里亚(Roseburia inulinivorans),其中含有编码Hydra水合酶(甘油脱水酶)的基因,该基因具有甘油衍生的丁酸梭状芽孢杆菌(Clostridium butyricumum),维生素B <与含有Hydra水合酶编码基因的重组微生物相比,源自Sub> 12依赖性甘油的3-HPA和3-HP生产表现出明显更好的活性。因此,本发明具有可以从培养物和培养微生物的3-HPA和3-HP中经济地大量获得的效果。 ;

著录项

  • 公开/公告号KR101494386B1

    专利类型

  • 公开/公告日2015-02-23

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120141124

  • 发明设计人 정원석;김낙종;최인석;이찬무;

    申请日2012-12-06

  • 分类号C12N1/21;C12N15/60;C12N15/53;C12P7/52;

  • 国家 KR

  • 入库时间 2022-08-21 14:58:39

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