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Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof
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机译:二唑及其衍生物与细胞结合分子的缀合物,新型二唑衍生物,其制备方法和用途
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摘要
The present invention provides conjugates of dithazolazole and derivatives thereof with, for example, cell binding molecules such as peptides or proteins, hormones, blood proteins and antibodies. The present invention also provides a novel dithazolazole derivative, a conjugate thereof, and a process for producing a dithazolazole derivative. These compounds can be used as medicaments for the treatment of physiological and / or pathophysiological conditions in mammals, particularly as medicaments for the treatment of various tumors. ; Dissolazoles, Dissolazole Derivatives, Cell Binding Molecules, Treatment of Tumors
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