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Prediction of the effectiveness of a medicament by means of 3d modeling in of the personalized medicine

机译:通过个性化药物的3D建模预测药物的有效性

摘要

The present invention relates to a process for the prediction of the effectiveness of a medicament in the case of a patient, wherein a nucleic acid sequence of a target molecule is determined, which interacts with the drug, and on the basis of the determined nucleic acid sequence a conformation of the target molecule is derived. By comparing the conformation of the target molecule with the conformation of a reference - target molecule the effectiveness of the medicament is predicted.
机译:本发明涉及在患者情况下预测药物有效性的方法,其中确定靶分子的核酸序列,所述靶分子与药物相互作用,并基于确定的核酸序列得到靶分子的构象。通过将靶分子的构象与参考-靶分子的构象进行比较,可以预测药物的有效性。

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