首页> 外国专利> PHARMACEUTICAL COMPOSITION CONTAINING LIRIODENDRON TULIPIFERA L. EXTRACT FOR TREATING CHRONIC MYELOGENOUS LEUKEMIA

PHARMACEUTICAL COMPOSITION CONTAINING LIRIODENDRON TULIPIFERA L. EXTRACT FOR TREATING CHRONIC MYELOGENOUS LEUKEMIA

机译：包含杜鹃花提取物的药物组合物，用于治疗慢性粒细胞性白血病

页面导航

摘要
著录项
相似文献

摘要

The present invention relates to a pharmaceutical composition containing, as an active ingredient, a Liriodendron tulipifera L. bark extract for treating chronic myelogneous leukemia. More specifically, the present invention relates to the pharmaceutical composition, containing, as the active ingredient, the Liriodendron tulipifera L. bark extract useful in selectively inhibiting mutant enzyme T315I from a mutation of a BCR-ABL fusion gene that causes chronic myelogenous leukemia, and to a use of epi-Tulipinolide which is an active ingredient of the composition.

机译：本发明涉及用于治疗慢性粒细胞白血病的药物组合物，其包含作为活性成分的鹅掌Li树皮提取物。更具体地，本发明涉及药物组合物，其包含作为活性成分的鹅掌Li树皮提取物作为活性成分，所述树皮提取物用于选择性地抑制突变酶T315I免受引起慢性粒细胞性白血病的BCR-ABL融合基因的突变的影响，以及表-Tulipinolide作为组合物的活性成分的用途。

著录项

公开/公告号EP2990046A1

专利类型
公开/公告日2016-03-02

原文格式PDF
申请/专利权人 CHO DANG PHARM. CO. LTD.;
展开▼

申请/专利号EP20140788947
发明设计人 KIM KI WOON;YOO HYE DONG;HONG SOON SUN;KIM SOO JUNG;LEE HYUN SEUNG;FANG ZHENGHUAN;KANG SU JIN;
展开▼

申请日2014-04-23
分类号A61K36/896;A61P35/02;
国家 EP
入库时间 2022-08-21 14:48:20

相似文献

专利
外文文献
中文文献

1. Cytotoxic effect of Spirulina platensis extracts on human acute leukemia Kasumi-1 and chronic myelogenous leukemia K-562 cell lines [J] . Flor Yohana Flores Hernandez, Sanghamitra Khandual 亚太热带生物医学杂志（英文版） . 2017,第001期

2. Cytotoxic effect of Spirulina platensis extracts on human acute leukemia Kasumi-1 and chronic myelogenous leukemia K-562 cell lines [J] . Flor Yohana Flores Hernandez, Sanghamitra Khandual, Inocencia Guadalupe Ramírez López 亚太热带生物医学杂志：英文版 . 2017,第001期

3. Optimization on Ultrasonic Extraction Method of Total Flavonoids for Liriodendron chinense Sarg.× L. tulipifera L. by Response Surface Methodology (RSM) [J] . Yi JIANG, Xuqin REN, Gang LI, 农业生物技术：英文版 . 2019,第005期

4. An EST database for Liriodendron tulipifera L. floral buds: the first EST resource for functional and comparative genomics in Liriodendron [J] . Haiying Liang, John E. Carlson, James H. Leebens-Mack, Tree Genetics & Genomes . 2008,第3期

5. Graft-versus-Leukemia (GVL) against Mouse Blast-Crisis Chronic Myelogenous Leukemia (BC-CML) and Chronic-Phase Chronic Myelogenous Leukemia (CP-CML): Shared Mechanisms of T Cell Killing, but Programmed Death Ligands Render CP-CML and Not BC-CML GVL Resistant [J] . Catherine Matte-Martone, Srividhya Venkatesan, Hung Sheng Tan, The journal of immunology . 2011,第4期

6. STRUCTURAL BIOLOGY CONTRIBUTIONS TO THE DISCOVERY OF DRUGS TO TREAT CHRONIC MYELOGENOUS LEUKEMIA [C] . SANDRA W. COWAN-JACOB, GABRIELE FENDRICH, ANDREAS FLOERSHEIMER, NATO Advanced Study Institute on From Molecules to Medicines: Integrating Crystallography in the Fight Against Bioterrorism and Emerging Diseases Affecting Security . 2009

7. Modeling Imatinib-Treated Chronic Myelogenous Leukemia and the Immune System [D] . Peters, Cara Disa. 2020

8. Complete Genome Sequence of Spiroplasma floricola 23-6T (ATCC 29989) a Bacterium Isolated from a Tulip Tree (Liriodendron tulipifera L.) [O] . Yi-Ming Tsai (蔡乙鳴), Pei-Shan Wu (吳佩珊), Wen-Sui Lo (羅文穗), 2018

9. Butadiene cancer exposure–response modeling: Based on workers in the styrene–butadiene–rubber industry: Total leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, and chronic myelogenous leukemia [O] . Sielken Robert L., Valdez-Flores Ciriaco 2011

10. Quantitative Risk Assessment of Exposures to Butadiene in European Union Occupational Settings Based on the University of Alabama at Birmingham Epidemiology Study: Acute Myelogenous Leukemia, Chronic Lymphocytic Leukemia, and Chronic Myelogenous Leukemia [R] . Silken, R. L., Valdez-Flores, C. 2007

1. Research on Marketing Strategies of Product D—a Chronic Myelogenous Leukemia Drug for Pharmaceutical Company A [J] . Gu Pu ,Wei Tingting ,Wu Zhi’ang . 亚洲社会药学 . 2020,第003期

2. Zeylenone promotes apoptosis of chronic myelogenous leukemia-derived K562 cells by a mechanism involving Jak2 and src kinase [J] . HUO Xiao-wei ,LIAO Yong-hong ,TIAN Yu . 中国药理学与毒理学杂志 . 2016,第10期

3. 张士舜用抗癌中药提取物及其组合治疗癌症经验 [C] . 李录花 ,李辉 ,方玉红 . 中华中医药学会2014年编辑出版分会年会暨中医、中西医结合防治肝病、肝癌高峰论坛 . 2014

4. 卷柏提取物作用于β-淀粉样蛋白的药物筛选 [A] . 戴璇 . 2013