Use of biomarkers in the evaluation of the initial transition from arterial hypertension to heart failure

摘要

PROBLEM TO BE SOLVED: To provide methods that predict a risk of an individual bearing risk factors of developing heart failure, to suffer from heart failure.;SOLUTION: A method of diagnosing functional and/or structural abnormalities of a heart preceding heart failure, in a subject bearing risk factors of developing heart failure, comprises the steps of: (a) measuring, in a sample obtained from an individual, concentration of at least one cardiac troponin; (b) optionally measuring, in the sample, concentration of one or more other marker(s) of heart failure; and (c) assessing functional and/or a structural abnormalities by comparing the concentration determined in the step (a) and optionally the concentration(s) determined in the step (b) with concentration of a marker or markers established in a control sample.;COPYRIGHT: (C)2015,JPO&INPIT