1-methylfolate treatment for psychiatric or neurological disorders.

摘要

1-methylfolate treatment for psychiatric or neurological disorders. Disclosed herein are methods of treating neuropsychiatric disorders or ameliorating the symptoms associated therewith with administering a medicinal food, such as 1-methylfolate, to a subject having the disorder. Neuropsychiatric treatment may be an autism spectrum disorder or attention deficit disorder with or without hyperactivity (add / adhd). 1-methylfolate may be administered as an adjunct to other effective therapeutic agents for treating the disorder. the subject may preferably be a child and may also have a single nucleotide polymorphism in the mthfr gene associated with reduced expression of the mthfr enzyme. Also provided is a method for increasing de novo synthesis of neurotransmitters in vivo by transporting a methyl-donor compound across an individual's brain blood barrier.