isolated antibody molecule for human il-18, composition, use of an antibody molecule, isolated nucleic acid molecule, host cell, and methods for producing an antibody and for measuring il-18

摘要

The present invention provides human, humanized and/or chimeric antibodies as well as fragments, derivatives/conjugates and compositions thereof with a specific binding affinity for interleukin-18. The invention includes the use of these antibodies for diagnosing and treating diseases associated with increased IL-18 activity, the latter in the form of a pharmaceutical composition.