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PROCESS FOR PRODUCING PARTICLES LOADED WITH GROWTH FACTORS, AND THE PARTICLES OBTAINED IN THIS WAY

机译:生产负载有生长因子的颗粒的过程,以及以此方式获得的颗粒

摘要

The present invention refers to a process for preparing a particulateinorganic materialloaded with growth factors, wherein said particulate material being selectedfrom ceramicmaterials is treated with growth factors in aqueous buffered solution in theacidic range betweenpH 4 and 5 over a period of at least 30 minutes, then the particulate materialis separated fromthe aqueous buffered solution and washed at least once with the same volume ofthe bufferedsolution free of growth factor, whereby an increased amount of growth factorwhich cannot bewashed off from the particle, is adsorbed to the surface, by means ofadsorption as a form ofchemical bonding.
机译:本发明涉及一种制备颗粒的方法无机材料填充有生长因子,其中所述颗粒材料被选择从陶瓷材料在生长缓冲液中用生长因子处理酸性范围在至少30分钟的时间内保持pH为4和5,然后是颗粒状物质与...分离缓冲水溶液,并用相同体积的缓冲的不含生长因子的溶液,从而增加了生长因子的量不能是从颗粒上洗掉,通过以下方式吸附到表面吸附形式化学键。

著录项

  • 公开/公告号CA2704123C

    专利类型

  • 公开/公告日2015-12-22

    原文格式PDF

  • 申请/专利权人 JENNISSEN HERBERT;

    申请/专利号CA20082704123

  • 发明设计人 JENNISSEN HERBERT;ZURLINDEN KRISTIN;

    申请日2008-10-29

  • 分类号A61L27/10;A61L27/42;A61L27/50;A61L27/56;

  • 国家 CA

  • 入库时间 2022-08-21 14:21:53

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