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IN SITU TESTING APPARATUS FOR INHALATION TOXICITY OF NANO PATICLES USING LUNG MODEL

机译:肺部模型对纳米颗粒吸入​​毒性的原位测试装置

摘要

The present invention relates to an apparatus for performing a real-time inhalation toxicity test using a lung model. More specifically, a lung model device capable of performing similar structure and function of a real lung is formed by attaching lung cells and the status change of the lung cells can be investigated without using experimental animals by detecting electric signals generated from the lung model device depending on the damage status of the lung cells due to the inhalation of nanoparticles. Hence, in the present invention, provided is an indirect method for testing the toxicity of nanoparticles.
机译:本发明涉及一种使用肺模型进行实时吸入毒性试验的设备。更具体地,通过附着肺细胞形成能够执行与真实肺相似的结构和功能的肺模型装置,并且通过检测由肺模型装置产生的电信号,可以不使用实验动物而研究肺细胞的状态变化。吸入纳米颗粒对肺细胞的损害状况因此,在本发明中,提供了一种用于测试纳米颗粒的毒性的间接方法。

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