首页>外文期刊>医学、药学、卫生>药学>Regulatory Toxicology and Pharmacology: RTP

Regulatory Toxicology and Pharmacology: RTP

Regulatory Toxicology and Pharmacology: RTP

SCIMEDLINE

中文名称：监管毒理学和药理学：RTP

ISSN：0273-2300
出版周期：-

发文量：2249

期刊论文

年度选择

2021
- 第1期
- 第1期
- 第1期
2020
- 第1期
- 第1期
- 第1期
- 第1期
- 第2020期
- 第2020期
2019
- 第1期
- 第2019期
- 第2019期
- 第2019期
- 第2019期
- 第2019期
- 第2019期
- 第2019期
- 第2019期
2018
- 第2018期
- 第2018期
- 第2018期
- 第2018期
- 第2018期
- 第2018期
- 第2018期
- 第2018期
- 第2018期
2017
- 第1期
- 第2期
- 第3期
- 第2017期
- 第2017期
- 第2017期
- 第2017期
- 第2017期
- 第2017期
- 第2017期
- 第2017期
2016
- 第1期
- 第1期
- 第2期
- 第2期
- 第2016期
- 第2016期
- 第2016期
- 第2016期
- 第2016期
- 第2016期
- 第2016期
- 第2016期
- 第2016期
- 第suppla期
2015
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2014
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2013
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2012
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2011
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
- 第2suppla期
2010
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2009
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2008
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
- 第3suppla期
2007
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2006
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2005
- 第1期
- 第1期
- 第1期
- 第2期
- 第2期
- 第2期
- 第3期
- 第3期
- 第3期
2004
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期
2003
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期
2002
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期
2001
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期
2000
- 第1期
- 第3期
- 第3期
1999
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期
1998
- 第1期
- 第1期
- 第2期
- 第2期
- 第3期
- 第3期

更多>>

全选（0）

1.Investigating toxicity specific to adjuvanted vaccines

机译：调查佐剂特异性疫苗的毒性
- 作者：Mineo Matsumoto;Shin-ichi Komatsu;Takanori Ikeda;Kazuhiro Shimomura;Kazuto Watanabe;Keiji Hirabayashi;Jun-ichi Sawada;Kazushige Maki;Kazutoshi Shinoda;Osamu Fueki;Hiroshi Onodera
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
2.Resolution of contradiction between in silico predictions and Ames test results for four pharmaceutically relevant impurities

机译：在硅预测和四种药学相关杂质中的硅预测和Ames测试结果之间的解决方案
- 作者：William C. Gunther;Michelle O. Kenyon;Jennifer R. Cheung;Robert W. Dugger;Krista L. Dobo
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Ames assay;
- Impurities;
- Mutagenicity;
- Micro colonies;
- In silico;
- ICHM7;
- Aromatic amines;
3.Safety assessment of transgenic canola RF3 with bar and barstar gene on Sprague-Dawley (SD) rats by 90-day feeding test

机译：通过90天进料试验对Sprague-Dawley（SD）大鼠杆和Barstar基因转基因Canola RF3的安全评估
- 作者：Tianqi Lang;Shiying Zou;Kunlun Huang;Mingzhang Guo;Xu Liu;Xiaoyun He
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Transgenic canola;
- Safety assessment;
- 90-Day feeding test;
- Gut microbiota;
4.Assessment of toxicity and tolerability of a combination vehicle; 5% Pharmasolve, 45% Propylene glycol and 50% Polyethylene glycol 400 in rats following repeated intravenous administration

机译：评估组合载体的毒性和耐受性; 在重复静脉内给药后，5％Pharmasolve，45％丙二醇和50％聚乙二醇400中的大鼠
- 作者：Santosh Kumar Pandey;Vinod Kumar Goyal;Prashant Nalge;Purnachander Are;Sthevaan Vincent;Ramakrishna Nirogi
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Propylene glycol (PG);
- Polyethylene glycol (PEG) 400;
- Pharmasolve (NMP);
- Combination vehicle;
- Tolerability;
- Safety;
- Rat;
5.Derivation of endogenous equivalent values to support risk assessment and risk management decisions for an endogenous carcinogen: Ethylene oxide

机译：衍生内源性等值，以支持内源性致癌物质的风险评估和风险管理决策：环氧乙烷
- 作者：C.R. Kirman;S.M. Hays
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Risk assessment;
- Risk management;
- Endogenous exposure;
- Biomarkers of exposure;
- Ethylene oxide;
- Point of departure;
6.Framework for the quantitative weight-of-evidence analysis of ‘omics data for regulatory purposes

机译：用于监管目的的OMICS数据的定量重量分析的框架
- 作者：Jim Bridges;Ursula G. Sauer;Roland Buesen;Lize Deferme;Knut E. Tollefsen;Tewes Tralau;Ben van Ravenzwaay;Alan Poole;Mark Pemberton
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Weight-of-evidence;
- Study quality (reliability);
- Data relevance;
- Regulatory toxicology;
- Hazard assessment;
- Mode-of-action;
- Strength of evidence;
7.Cellular and functional actions of tofacitinib related to the pathophysiology of hibernoma development

机译：TOFACITINIB的细胞和功能作用与血脂瘤发展的病理生理学相关
- 作者：Zaher A. Radi;W. Mark Vogel;Phillip M. Bartholomew;Petra Koza-Taylor;Alexandros Papanikolaou;Todd Wisialowski;Prashant Nambiar;Douglas J. Ball
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Hibernoma;
- JAK inhibition;
- pSTAT;
- Sympathetic stimulation;
- Tofacitinib;
8.Weight of evidence approaches for the identification of endocrine disrupting properties of chemicals: Review and recommendations for EU regulatory application

机译：鉴定化学物质的内分泌破坏性质的验证方法的重量：审查和建议欧盟监管申请
- 作者：Melanie Gross;Richard M. Green;Lennart Weltje;James R. Wheeler
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Endocrine disrupting properties;
- Weight of evidence;
- Mode of action;
- Adverse outcome pathway;
9.Proposal of a flow scheme for the chemical-form-based quantitative analysis of chlorine compounds in pulp for sanitary products and verification of safety

机译：基于化学形式的化学形式的定量分析的流动方案的提议，用于卫生产品的纸浆中的氯化合物和安全性验证
- 作者：Takeharu Wada;Kei Iwasaki;Yasushi Minobe;Mitsuhiro Wada;Shigeo Imai;Satoko Ishii
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Water-soluble chlorides;
- Insoluble organically bound chlorine;
- Sanitary product;
- Pulp;
- ECF;
- Bleaching;
- GC-MS;
- Dermal exposure;
10.Influence of cigarette filter ventilation on smokers’ mouth level exposure to tar and nicotine

机译：卷烟过滤器通风对吸烟者口水平暴露于焦油和尼古丁的影响
- 作者：John W. Caraway;Madeleine Ashley;Sheri A. Bowman;Peter Chen;Graham Errington;Krishna Prasad;Paul R. Nelson;Christopher J. Shepperd;Ian M. Fearon
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Cigarette;
- Filter ventilation;
- Mouth level exposure;
- Tar;
- Nicotine;
11.Assessment of predictivity of volatile organic compounds carcinogenicity and mutagenicity by freeware in silico models

机译：用硅模型中自由的自由用品评估挥发性有机化合物致癌性和致突变性的预测性
- 作者：Lília Ribeiro Guerra;Alessandra Mendon?a Teles de Souza;Juliana Alves C?rtes;Viviane de Oliveira Freitas Lione;Helena Carla Castro;Gutemberg Gomes Alves
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Computational toxicology;
- In silicomethods;
- QSAR;
- Carcinogenicity;
- Mutagenicity;
12.The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook

机译：“OMICS技术”在化学品风险评估中的应用挑战：背景与展望
- 作者：Ursula G. Sauer;Lize Deferme;Laura Gribaldo;J?rg Hackermüller;Tewes Tralau;Ben van Ravenzwaay;Carole Yauk;Alan Poole;Weida Tong;Timothy W. Gant
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
13.Editorial: Applying ‘omics technologies in chemicals risk assessment

机译：社论：在化学品风险评估中应用'OMICS技术
- 作者：Bennard van Ravenzwaay;Ursula G. Sauer;Olivier de Matos
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
14.Non-clinical efficacy-related studies for human medicines: An overview and retrospective analysis of data for a group of approved medicines

机译：对人类药物的非临床疗效相关研究：概述和回顾一组批准的药物数据
- 作者：Ana Cláudia Figueiredo
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Efficacy;
- Drug development;
- Cancer;
- Animal studies;
- In?vitrostudies;
- Monoclonal antibodies;
- Anticancer medicines;
- Clinical development;
- Preclinical studies;
15.Guidelines for performing systematic reviews in the development of toxicity factors

机译：在毒性因素的发展中表演系统审查的指导方针
- 作者：Heather R. Schaefer;Jessica L. Myers
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Systematic review;
- Risk assessment;
- Regulatory toxicology;
16.Studies on the environmental fate, ecotoxicology and toxicology of 2-methyl 1,3-propanediol

机译：对1,3-丙二醇的环境命运，生态毒理学和毒理学研究
- 作者：J. Fowles;C. Lewis;E. Rushton
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- 2-methyl 1;
- 3-propandiol;
- Toxicology;
- Ecotoxicology;
- Environmental fate;
- Regulatory toxicology;
17.Framework for the quality assurance of ’omics technologies considering GLP requirements

机译：考虑GLP要求的OMICS技术质量保证的框架
- 作者：Hans-Martin Kauffmann;Hennicke Kamp;Regine Fuchs;Brian N. Chorley;Lize Deferme;Timothy Ebbels;J?rg Hackermüller;Stefania Perdichizzi;Alan Poole;Ursula G. Sauer;Knut E. Tollefsen;Tewes Tralau;Carole Yauk;Ben van Ravenzwaay
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
18.Acute and subchronic toxicity studies of seabuckthorn ( Hippophae rhamnoides L.) oil in rodents

机译：啮齿动物急性和次曲调毒性研究Seabuckthorn（Hippophae rhamnoides L.）油的毒性研究
- 作者：Peng Zhao;Shaolong Wang;Chuan Liang;Yanwu Wang;Pingjing Wen;Fang Wang;Guangqiu Qin
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Hippophae rhamnoides;
- Seabuckthorn oil;
- Subchronic toxicity;
- Safety;
19.Making sense of SEND; the Standard for Exchange of Nonclinical Data

机译：送送礼; 非界性数据交换的标准
- 作者：Katharine Briggs
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- SEND;
- KNIME;
- Open access;
- Data mining;
- eTOX;
20.Table of Contents

机译：目录
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
21.Acute and a 28-day repeated-dose toxicity study of total flavonoids from Clinopodium chinense (Benth.) O. Ktze in mice and rats

机译：急性和28天的反复剂量毒性研究来自Clinopodium Clinensium（Benth。）O. Ktze的小鼠和大鼠
- 作者：Yonglin Gao;Yunzhi Wang;Kezhou Wang;Jing Zhu;Guisheng Li;Jingwei Tian;Chunmei Li;Zhenhua Wang;Ji Li;Albert W. Lee;Chenghua Guo
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Total flavonoids fromClinopodium chinense(Benth.) O. Ktze (TFCC);
- Acute toxicity;
- Subacute toxicity;
- Mice;
- Rats;
22.The relationship of snus use to diabetes and allied conditions

机译：Snus对糖尿病和盟友的关系
- 作者：Peter N. Lee;Alison J. Thornton
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Diabetes;
- Tobacco;
- Smokeless;
23.Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

机译：在化学品风险评估中应用“OMICS技术”：ECETOC研讨会的报告
- 作者：Roland Buesen;Brian N. Chorley;Beatriz da Silva Lima;George Daston;Lize Deferme;Timothy Ebbels;Timothy W. Gant;Amber Goetz;John Greally;Laura Gribaldo;J?rg Hackermüller;Bruno Hubesch;Danyel Jennen;Kamin Johnson;Jun Kanno;Hans-Martin Kauffmann;Madeleine Laffont;Patrick McMullen;Richard Meehan;Mark Pemberton;Stefania Perdichizzi;Aldert H. Piersma;Ursula G. Sauer;Kerstin Schmidt;Hervé Seitz;Kayo Sumida;Knut E. Tollefsen;Weida Tong;Tewes Tralau;Ben van Ravenzwaay;Ralf J.M. Weber;Andrew Worth;Carole Yauk;Alan Poole
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
24.On selecting a minimal set of in?vitro assays to reliably determine estrogen agonist activity

机译：在选择最小一组的体外测定以可靠地确定雌激素激动剂活性
- 作者：Richard S. Judson;Keith A. Houck;Eric D. Watt;Russell S. Thomas
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Endocrine disruption;
- Estrogen receptor;
- Alternative testing methods;
- In?vitro;
25.A new approach for risk assessment of aggregate dermal exposure to banned azo dyes in textiles

机译：纺织品禁区含氮杂染料的综合皮肤暴露风险评估新方法
- 作者：Xuezhang Chen;Qixi Deng;Shubao Lin;Chao Du;Shengqiao Zhao;Yongjie Hu;Zhongguo Yang;Yanhui Lyu;Jianjian Han
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Azo dyes;
- Textile;
- Aromatic amines;
- Risk assessment;
26.Table of Contents

机译：目录
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
27.Toxicity assessment of pesticide triclosan by aquatic organisms and degradation studies

机译：水生生物和降解研究毒性评估农药三氯联
- 作者：Burcu Ertit Ta?tan;Turgay Tekinay;Hatice Sena ?elik;Caner ?zdemir;Dilara Nur Cakir
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Biodegradation;
- Cyanobacteria;
- Microalgae;
- Toxicity;
- Triclosan;
- 2;
- 4-Dichlorophenol;
28.Safety investigation on total steroid saponins extracts from Dioscorea zingiberensis C.H. Wright: Sub-acute and chronic toxicity studies on dogs

机译：Zingiberensis C.h.的类固醇皂苷类别皂苷的安全性研究。赖特：狗急性和慢性毒性研究
- 作者：Xinxin Zhang;Ming Jin;Nigatu Tadesse;Liang Xian;Hui Zhang;Sicen Wang;Jun Dang;Yan Zhang;Zengjun Guo;Yoichiro Ito
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Dioscorea zingiberensisC.H. Wright;
- Steroid saponins;
- Sub-acute toxicity;
- Chronic toxicity;
29.Safety evaluation of auraptene in rats in acute and subacute toxicity studies

机译：急性和亚急性毒性研究大鼠氮素的安全评价
- 作者：Tooraj Vakili;Mehrdad Iranshahi;Hosseinali Arab;Bamdad Riahi;Nama Mohammadian Roshan;Gholamreza Karimi
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Auraptene;
- Acute toxicity;
- Subacute toxicity;
- Immunotoxicity;
30.Cigar burning under different smoking intensities and effects on emissions

机译：在不同的吸烟强度下燃烧雪茄燃烧和对排放的影响
- 作者：Ole Dethloff;Christian Mueller;Xavier Cahours;Stéphane Colard
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Cigar smoking;
- Cigar emissions;
- Cigar;
- Product comparison;
- Cigar burning;
31.Neuropharmacological and acute toxicological evaluation of ethanolic extract of Allamanda cathartica L. flowers and plumieride

机译：AllaManda Cathartica L.乙醇提取物的神经药理学和急性毒理学评估
- 作者：Tiago J. Bonomini;Iandra Holzmann;Liliani Carolini Thiesen;Eduarda Fratoni;Ana Flavia Fischer Muller;Ruth M. Lucinda-Silva;Rosendo Augusto Yunes;Angela Malheiros;Ana Elisa Gon?alves;Ana Paula Dalmagro;Kathryn Ana Bortolini Sim?o da Silva;Márcia Maria de Souza;José Roberto Santin
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Allamanda cathartica;
- Toxicity;
- Antidepressant-like effect;
- Plumieride;
32.Cover 2--Editorial Board

机译：封面2 - 编辑委员会
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
33.Cover 2--Editorial Board

机译：封面2 - 编辑委员会
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
34.Application of in vitro skin penetration measurements to confirm and refine the quantitative skin sensitization risk assessment of methylisothiazolinone

机译：在体外皮肤渗透测量中的应用来证实和优化甲基噻唑啉酮的定量皮肤致敏风险评估
- 作者：Helga Rothe;Cindy A. Ryan;Leanne Page;Joanne Vinall;Carsten Goebel;Heike Scheffler;Frank Toner;Clive Roper;Petra S. Kern
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Methylisothiazolinone;
- Quantitative-risk-assessment;
- Measured exposure levels;
- Skin penetration;
- Cosmetics;
- Household care;
- Consumer;
- Skin sensitization;
35.Safety evaluation of supratherapeutic dose of Maytenus ilicifolia Mart. ex Reissek e xtracts on fertility and neurobehavioral status of male and pregnant rats

机译：梅霉素伊锡伊斯坦岛伊思米紫外梅的安全评价。 EX REISSEK E XTRACTS对男性和怀孕大鼠的生育和神经兽性地位
- 作者：Assis Ecker;Carla Giane Loss;Stephen A. Adefegha;Aline Augusti Boligon;Silvane Souza Roman
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Maytenus ilicifolia;
- Pregnancy;
- Neurobehavioral;
- Fertility;
36.Applicability of in silico genotoxicity models on food and feed ingredients

机译：在食品和饲料成分上硅基毒性模型的适用性
- 作者：Anna Vuorinen;Phillip Bellion;Paul Beilstein
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Food ingredient;
- Feed ingredient;
- Computational toxicology;
- In silico;
- Genotoxicity;
- Ames;
- Micronucleus test;
- Chromosomal aberration;
37.Evaluation of airborne sensory irritants for setting exposure limits or guidelines: A systematic approach

机译：用于设定曝光限制或指南的空气传播刺激物的评估：系统方法
- 作者：Gunnar Damgaard Nielsen;Peder Wolkoff
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Alarie test;
- Animals;
- Chemesthesis;
- Evaluation;
- Humans;
- Mice;
- Sensory irritation;
38.Subchronic toxicity study of yttrium nitrate by 90-day repeated oral exposure in rats

机译：大鼠亚硝酸钇钇氮酸盐毒性研究
- 作者：Yi-Mei Wang;Zhou Yu;Zeng-Ming Zhao;Li Jia;Hai-Qin Fang;Ting-Fen Zhang;Xiao-Yan Yuan;Yu-Lei Shu;Jun He;Hui Peng;Li-Zhong Li;Jun Zhao;Xu-Dong Jia;Shuang-Qing Peng
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Rare earth elements;
- ADI;
- Yttrium;
- Subchronic toxicity;
- NOAEL;
39.In?vitro method to evaluate the barrier properties of medical devices for cutaneous use

机译：在体外方法中评估医疗器械的阻隔性，以进行皮肤使用
- 作者：Antonella Casiraghi;Francesco Ranzini;Umberto M. Musazzi;Silvia Franzè;Marisa Meloni;Paola Minghetti
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
40.Establishing maximum tolerated doses for a 2-year combined chronic/carcinogenicity rat study based on toxicokinetic and toxicity gender differences

机译：基于毒物动力学和毒性性别差异建立2年综合慢性/致癌性大鼠研究的最大耐受剂量
- 作者：Zhiwei Liu;Amanda Wasniewski;Sara Lamperti;Katia Mainolfi;Appavu Chandrasekaran
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Maximum tolerated dose;
- Chronic toxicity;
- Carcinogenicity;
- Toxicokinetics;
- Gender difference;
41.Dermal absorption for pesticide health risk assessment: Harmonization of study design and data reporting for North American Regulatory submissions

机译：农药健康风险评估的皮肤吸收：北美监管意见书的研究设计与数据报告
- 作者：Kristie M. Sullivan;Manoj Aggarwal;Jonathan M. Akins;Eric Fabian;Jon R. Heylings;Hans Raabe;Prakashchandra (P.V.) Shah;Christiane Wiemann;Richard Peffer
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- In?vitro;
- Dermal absorption;
- Pesticide;
- Risk assessment;
- North America;
- Triple-pack;
- Human;
42.7-Chloro-4-phenylsulfonyl quinoline, a new antinociceptive and anti-inflammatory molecule: Structural improvement of a quinoline derivate with pharmacological activity

机译：7-氯-4-苯磺酰喹啉，一种新的抗血质和抗炎分子：用药理学活性喹啉衍生的结构改善
- 作者：Mikaela P. Pinz;Angélica S. Reis;Renata Leivas de Oliveira;Guilherme T. Voss;Ane G. Vogt;Manoela do Sacramento;Juliano A. Roehrs;Diego Alves;Cristiane Luchese;Ethel A. Wilhelm
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Nociception;
- Inflammation;
- Quinoline;
- Sulfone;
- Mice;
43.Silver nanoparticles protect acetaminophen induced acute hepatotoxicity: A biochemical and histopathological approach

机译：银纳米粒子保护乙酰氨基酚诱导急性肝毒性：生物化学和组织病理学方法
- 作者：Mohd Salim Reshi;Chhavi Uthra;Deepa Yadav;Samta Sharma;Asha Singh;Anjali Sharma;Amita Jaswal;Neelu Sinha;Sadhana Shrivastava;Sangeeta Shukla
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Silver nanoparticles;
- Hepatoprotection;
- Acetaminophen;
44.Cleaning and asthma: A systematic review and approach for effective safety assessment

机译：清洁和哮喘：有效安全评估的系统审查和方法
- 作者：Melissa J. Vincent;Ann Parker;Andrew Maier
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Asthma;
- Hazard characterization;
- Cleaning;
- Systematic review;
- Acetic acid;
- Weight of evidence;
- Sensitization;
- Irritation;
45.Chemical-induced asthma and the role of clinical, toxicological, exposure and epidemiological research in regulatory and hazard characterization approaches

机译：化学诱导的哮喘和临床，毒理学，暴露和流行病学研究的作用，监管和危险表征方法
- 作者：Melissa J. Vincent;Jonathan A. Bernstein;David Basketter;Judy S. LaKind;G. Scott Dotson;Andrew Maier
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Asthma;
- Hazard characterization;
- Respiratory sensitization;
- Consumer products;
- Risk management;
46.Toxicological evaluation of neoagarooligosaccharides prepared by enzymatic hydrolysis of agar

机译：琼脂酶水解制备的新卤代洛尼糖的毒理学评价
- 作者：Sun Joo Hong;Je-Hyeon Lee;Eun Joo Kim;Hea Jung Yang;Jae-Seon Park;Soon-Kwang Hong
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- NAOs (neoagarooligosaccharides);
- Acute toxicity;
- Subchronic toxicity;
- Genotoxicity;
- Agar;
47.Acute oral toxicity study of magnesium oxide nanoparticles and microparticles in female albino Wistar rats

机译：慢性氧化物纳米粒子和微粒在雌性白化Wistar大鼠中的急性口腔毒性研究
- 作者：Bhanuramya Mangalampalli;Naresh Dumala;Paramjit Grover
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Magnesium oxide nanoparticles;
- Wistar rats;
- Genotoxicity;
- Biodistribution;
- Antioxidant assays;
- Hematological alterations;
48.Acute and subacute toxicities of biogenic tellurium nanorods in mice

机译：小鼠生物碲纳米棒的急性和亚急性毒性
- 作者：Sara Najimi;Mojtaba Shakibaie;Elham Jafari;Atefeh Ameri;Nazanin Rahimi;Hamid Forootanfar;Mahnaz Yazdanpanah;Hamid Reza Rahimi
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Lethal dose;
- Biogenic Te nanorods;
- Oxidative stress;
- Nanotoxicity;
49.Safety evaluation for ingredients used in baby care products: Consideration of diaper rash

机译：婴儿护理产品中使用的成分的安全评估：尿布皮疹的考虑
- 作者：Susan P. Felter;Andrew N. Carr;Tingting Zhu;Taryn Kirsch;Gloria Niu
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Diaper rash;
- Compromised skin;
- Dermal penetration;
- Safety assessment;
- Risk assessment;
50.Toxicological profile of IQG-607 after single and repeated oral administration in minipigs: An essential step towards phase I clinical trial

机译：MINIPIGS单身和重复口服给药后IQG-607的毒理学概况：迈向I临床试验的重要步骤
- 作者：Valnês S. Rodrigues-Junior;Luciana Cintra;Pablo Machado;Adílio Dadda;Luiz Augusto Basso;Ana Carolina Cintra Nunes Mafra;Alexandre Holthausen Campos;Maria Martha Campos;Diógenes Santiago Santos
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Tuberculosis;
- IQG-607;
- Drug development;
- Preclinical toxicology;
- Minipig;
51.Cover 2--Editorial Board

机译：封面2 - 编辑委员会
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
52.Oral mucosal irritation study in hamster to evaluate a therapeutic apparatus using hydrogen peroxide photolysis for periodontitis treatment

机译：仓鼠口腔粘膜刺激研究评价使用过氧化氢光解的治疗装置进行牙周炎治疗
- 作者：Yoshimi Niwano;Kazunori Konno;Takeshi Matayoshi;Keisuke Nakamura;Taro Kanno;Keiichi Sasaki
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Hydrogen peroxide;
- Photolysis;
- Hydroxyl radicals;
- Periodontal therapy;
- Oral mucosa irritation;
- Hamster;
53.Hazard characterization of an anti-human tissue factor antibody by combining results of tissue cross-reactivity studies and distribution of hemorrhagic lesions in monkey toxicity studies

机译：通过组织交叉反应性研究结果结合猴毒性研究的组织交叉反应性研究结果的危害表征抗人类组织因子抗体
- 作者：Etsuko Fujii;Kazuto Watanabe;Kaori Nishihara;Masami Suzuki;Atsuhiko Kato
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Tissue cross-reactivity study;
- Therapeutic antibody;
- Tissue factor;
- Target antigen;
- Hemorrhagic lesion;
- Hazard characterization;
54.Development of a tool to assess the completeness of drug information sources for health care professionals: A Delphi study

机译：开发一种评估药物信息来源的完整性卫生保健专业人士的工具：Delphi研究
- 作者：Blanca Arguello;Teresa M. Salgado;Gert Laekeman;Fernando Fernandez-Llimos
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Clinical decision support systems;
- Delphi technique;
- Drug information;
- Drug labelling;
55.Bisphenol A and immunotoxic potential: A commentary

机译：双酚A和免疫毒性潜力：评论
- 作者：Ian Kimber
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Bisphenol A;
- Immunotoxicity;
- Allergy;
- Immunological tolerance;
56.Fish cell lines as a tool for the ecotoxicity assessment and ranking of engineered nanomaterials

机译：鱼细胞系作为生态毒性评估和工程纳米材料排名的工具
- 作者：A. Bermejo-Nogales;M.L. Fernández-Cruz;J.M. Navas
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Engineered nanomaterials;
- Cell lines;
- Cytotoxicity;
- Hazard ranking;
- Nanomaterial grouping;
- Fish;
- IATA;
57.Genotoxicity and sub-chronic toxicity of MYOLUTION ? (branched chain keto acids)

机译：肌肉的遗传毒性和亚慢性毒性？（支链酮酸）
- 作者：Caroline Hall;Ian Grayson
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- BCKA;
- Branched chain keto acids;
- Keto-leucine;
- Keto-isoleucine;
- Keto-valine;
- MYOLUTION?;
- Food additive;
- Genotoxicity;
- Repeated dose toxicity;
- Sub-chronic toxicity;
58.Citrus aurantium (bitter orange) extract: Safety assessment by acute and 14-day oral toxicity studies in rats and the Ames Test for mutagenicity

机译：柑橘耳静脉（苦橙）提取物：大鼠急性和14天口服毒性研究的安全评估和诱变诱变的AMES
- 作者：N.S. Deshmukh;S.J. Stohs;C.C. Magar;S.B. Kadam
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Citrus aurantium;
- Bitter orange;
- p-synephrine;
- Safety;
- LD50;
- Ames Test;
- Salmonella typhimurium;
- Reverse mutation assay;
59.An FDA oncology analysis of CD3 bispecific constructs and first-in-human dose selection

机译：CD3双特异性构建的FDA肿瘤学分析及一体化剂量选择
- 作者：Haleh Saber;Pedro Del Valle;Tiffany K. Ricks;John K. Leighton
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- CD3 bispecific;
- MABEL;
- First-in-human dose;
- Oncology drug development;
60.In chemico, in?vitro and in?vivo comparison of the skin sensitizing potential of eight unsaturated and one saturated lipid compounds

机译：在Chemico中，在体外和α体内比较八个不饱和和一种饱和脂质化合物的皮肤敏化潜力
- 作者：Reinhard Kreiling;Helge Gehrke;Thomas H. Broschard;Birte Dree?en;Dorothea Eigler;David Hart;Veronika H?pflinger;Marcus Kleber;Joanna Kupny;Qiang Li;Peter Ungeheuer;Ursula G. Sauer
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
61.A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies

机译：一个联盟驱动的框架，指导ICH M7选项4控制策略的实施
- 作者：Chris Barber;Vincent Antonucci;Jens-Christoph Baumann;Roland Brown;Elizabeth Covey-Crump;David Elder;Eric Elliott;Jared W. Fennell;Fabrice Gallou;Nathan D. Ide;Guido Jordine;Jeffrey M. Kallemeyn;Dirk Lauwers;Adam R. Looker;Lucie E. Lovelle;Mark McLaughlin;Robert Molzahn;Martin Ott;Didier Schils;Rolf Schulte Oestrich;Neil Stevenson;Pere Talavera;Andrew Teasdale;Michael W. Urquhart;David L. Varie;Dennie Welch
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- ICH M7;
- Expert review;
- Purge;
- Mutagenic impurity;
- Purge Ratio;
- Mirabilis;
62.Effect of maternal feed restriction on prenatal development in rats and rabbits – A review of published data

机译：母体饲料限制对大鼠产前发育的影响 - 发布数据的综述
- 作者：Dana Nitzsche
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Feed restriction;
- Developmental toxicity;
- Rat;
- Rabbit;
- Classification;
63.The added value of the 90-day repeated dose oral toxicity test for industrial chemicals with a low (sub)acute toxicity profile in a high quality dataset: An update

机译：90天重复剂量口服毒性试验的增加值，用于高质量数据集中低（亚）急性毒性曲线的工业化学品：更新
- 作者：Katy Taylor;David J. Andrew
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Repeated dose;
- Low toxicity;
- REACH;
- Sub-acute;
- Oral;
- European Chemicals Agency;
64.Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette

机译：评估修改的风险烟草和尼古丁产品：科学框架的描述和闭合模块化电子烟的评估
- 作者：James Murphy;Marianna Gaca;Frazer Lowe;Emmanuel Minet;Damien Breheny;Krishna Prasad;Oscar Camacho;Ian M. Fearon;Chuan Liu;Christopher Wright;Kevin McAdam;Christopher Proctor
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Tobacco harm reduction;
- Modified Risk Tobacco Products;
- Public health;
- Risk reduction;
- Assessment framework;
65.Comparative assessment of HPHC yields in the Tobacco Heating System THS2.2 and commercial cigarettes

机译：烟草加热系统中HPHC产量的比较评估及商业卷烟
- 作者：G. Jaccard;D. Tafin Djoko;O. Moennikes;C. Jeannet;A. Kondylis;M. Belushkin
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Harmful and potentially harmful constituents;
- Modified risk tobacco products;
- Tobacco Heating System;
- THS 2.2;
66.Table of Contents

机译：目录
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
67.Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

机译：调查基于生理学的动力学建模实践和挑战，与增加模型应用的监管
- 作者：Alicia Paini;Jeremy A. Leonard;Tomas Kliment;Yu-Mei Tan;Andrew Worth
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- PBK models;
- Physiologically based kinetic models;
- Regulatory;
- Toxicology;
- Risk assessment;
- Alternatives methods;
68.A quantitative weight of evidence assessment of confidence in modes-of-action and their human relevance

机译：定量重量的证据评估对行为方式及其相关性的信心
- 作者：Wolfgang Dekant;James Bridges;Anthony R. Scialli
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Weight of evidence;
- Mode of action;
- Reproductive toxicity;
- Systematic analysis;
69.Oligonucleotide-based pharmaceuticals: Non-clinical and clinical safety signals and non-clinical testing strategies

机译：基于寡核苷酸的药物：非临床和临床安全信号和非临床测试策略
- 作者：Enni-Kaisa Mustonen;Tiina Palom?ki;Markku Pasanen
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Antisense oligonucleotide;
- siRNA;
- Aptamer;
- Toxicity;
- Immunostimulation;
- Immunosuppression;
- Pharmacokinetics;
- Non-clinical;
70.Erratum to “A dynamic population model for estimating all-cause mortality due to lifetime exposure history” [Regul. Toxicol. Pharmacol. 67 (2013) 246–251]

机译：错误到“估计由于寿命曝光史导致的全因死亡率的动态人口模型”[法规。毒素。药狼。 67（2013）246-251]
- 作者：Annette M. Bachand;Sandra I. Sulsky
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
71.Acute toxicity, 28-day repeated-dose toxicity and toxicokinetic study of timosaponin BII in rats

机译：急性毒性，28天的重复剂量毒性和大鼠Timosaponin Bui的毒性研究
- 作者：Ni Lin;Baofeng Liu;Jie Zhang;Yongpeng Long;Guoming Dong;Hongtao Jin;Baiping Ma
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Timosaponin BII;
- Toxicity;
- Toxicokinetics;
- NOAEL;
- Rats;
72.In?vitro toxicological assessment of Arrabidaea brachypoda (DC.) Bureau: Mutagenicity and estrogenicity studies

机译：在Arrabidaea Broachypoda（DC.）局的体外毒理学评估：致突变性和雌激素研究
- 作者：Flávia Aparecida Resende;Catarine Haidê Nogueira;Lívia Greghi Espanha;Paula Karina Boldrin;Ana Paula Oliveira-H?hne;Mariana Santoro de Camargo;Cláudia Quintino da Rocha;Wagner Vilegas;Eliana Aparecida Varanda
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Arrabidaea brachypoda;
- Ames test;
- Recombinant yeast assay (RYA);
- Medicinal plants;
73.How well can carcinogenicity be predicted by high throughput “characteristics of carcinogens” mechanistic data?

机译：通过高通量的“致癌物体”机械数据来预测致癌性的程度如何？
- 作者：Richard A. Becker;David A. Dreier;Mary K. Manibusan;Louis A. (Tony) Cox;Ted W. Simon;James S. Bus
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Cancer hazard classification;
- IARC;
- Cancer prediction modeling;
- High throughput screening (HTS);
74.Framework for assessing causality of air pollution-related health effects for reviews of the National Ambient Air Quality Standards

机译：评估空气污染相关健康影响因果关系的框架，以审查国家环境空气质量标准
- 作者：Owens Elizabeth Oesterling;Patel Molini M.;Kirrane Ellen;Long Thomas C.;Brown James;Cote Ila;Ross Mary A.;Dutton Steven J.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Criteria air pollutants;
- Causal determination;
- Hazard identification;
- National Ambient Air Quality Standards;
75.Comparative assessment of immune complex-mediated hypersensitivity reactions with biotherapeutics in the non-human primate: Critical parameters, safety and lessons for future studies

机译：对非人灵长类动物的生物治疗剂免疫复合介导的过敏反应的比较评估：未来研究的关键参数，安全和课程
- 作者：Kronenberg Sven;Husar Elisabeth;Schubert Christine;Freichel Christian;Emrich Thomas;Lechmann Martin;Giusti Anna Maria;Regenass Franziska
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Biopharmaceuticals;
- Biotherapeutics;
- Non-clinical safety;
- Hypersensitivity;
- Immunogenicity;
- Immune complex;
- Monoclonal antibodies;
- Risk mitigation;
- Non-human primate;
76.Report of Morinda citrifolia chronic toxicity not applicable to commercial noni juice

机译：Morinda Citrifolia的报告慢性毒性不适用于商业诺米汁
- 作者：West Brett J.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
77.Response to Loomis et al Comment on Boobis et al

机译：对Boobis等人评论的回应
- 作者：Boobis Alan R.;Cohen Samuel M.;Dellarco Vicki L.;Doe John E.;Fenner-Crisp Penelope A.;Moretto Angelo;Pastoor Timothy P.;Schoeny Rita S.;Seed Jennifer G.;Wolf Douglas C.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
78.Utility of published DNA reactivity alerts

机译：发表的DNA反应性警报的效用
- 作者：Myden Alun;Guesne Sebastien J.;Cayley Alex;Williams Richard V.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Mutagenicity;
- Ames test;
- Expert review;
- Derek Nexus;
- Sarah Nexus;
- ICH M7;
- QSAR;
79.A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis

机译：一个12周随机临床试验研究了蔗糖影响葡萄糖稳态的可能性
- 作者：Grotz V. Lee;Pi-Sunyer Xavier;Porte Daniel Jr.;Roberts Ashley;Trout J. Richard
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Sucralose;
- Glucose homeostasis;
- OGTT;
- Healthy volunteers;
80.Azo dyes in clothing textiles can be cleaved into a series of mutagenic aromatic amines which are not regulated yet

机译：服装纺织品中的偶氮染料可以切割成一系列不受调控的诱变芳族胺
- 作者：Bruschweiler Beat J.;Merlot Cedric
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Textile dyes;
- Azo dyes;
- Aromatic amines;
- Mutagenicity;
- Ames test;
- In silico prediction;
81.Proarrhythmic risk assessment using conventional and new in vitro assays

机译：使用常规和新的体外测定进行预训练风险评估
- 作者：Goineau Sonia;Castagne Vincent
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
82.Safety evaluation of water-soluble palm fruit bioactives

机译：水溶性棕榈果生物果实的安全评估
- 作者：Lynch Barry S.;West Spencer;Roberts Ashley
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Oil palm;
- Polyphenols;
- Toxicity;
- Rat;
- Genotoxicity;
- Safety;
83.Mercury contamination in facial skin lightening creams and its health risks to user

机译：汞污染在面部皮肤遮光面霜及其对用户的健康风险
- 作者：Ho Yu Bin;Abdullah Nor Hidayu;Hamsan Hazwanee;Tan Eugenie Sin Sing
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Mercury;
- Cold vapor atomic absorption spectrometrym (CV-AAS);
- Hazard quotient (HQ);
84.Opinion of the scientific committee on consumer safety (SCCS) - Final version of the opinion on Ethylzingerone - 'Hydroxyethoxyphenyl Butanone' (HEPB) - Cosmetics Europe No P98-in cosmetic products

机译：消费者安全科学委员会（SCCS） - 最终版本的乙基辛酮 - '羟基乙氧基苯基丁酮'（HEPB） - 化妆品欧洲无P98-化妆品
- 作者：Bernauer Ulrike
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- SCCS;
- Scientific opinion;
- Ethylzingerone;
- 'Hydroxyethoxyphenyl Butanone' (HEPB);
- Cosmetics Europe No P98;
- Regulation 1223/2009;
- CAS 569646-79-3;
85.Repeated dose 28-day oral toxicity study of DEAE-Dextran in mice: An advancement in safety chemotherapeutics

机译：反复剂量28天口服毒性研究小鼠的DEAE-DEEXTRAN：安全化学治疗方法的进步
- 作者：Bakrania Anita K.;Variya Bhavesh C.;Madan Prem;Patel Snehal S.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Oral toxicity;
- DEAE-Dextran;
- OECD 407;
- Gross necropsy;
- Gross histopathology;
86.Air quality and acute deaths in California, 2000-2012

机译：加利福尼亚州的空气质量和急性死亡，2000-2012
- 作者：Young S. Stanley;Smith Richard L.;Lopiano Keneth K.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Air quality;
- Air pollution;
- PM2.5;
- Ozone;
- Acute deaths;
- Time series regression;
- Mortality;
87.Itching for change: Embracing modern flea and tick product development

机译：改变瘙痒：拥抱现代跳蚤和蜱产品开发
- 作者：Groff Katherine;Bishop Patricia
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Fleas;
- Ticks;
- Dogs;
- Cats;
- Product testing;
- Ectoparasiticides;
- In vitro feeding;
88.Binary test battery with KeratinoSensTM and h-CLAT as part of a bottom-up approach for skin sensitization hazard prediction

机译：二元测试电池与角鲨素和H-Clat作为皮肤敏感危害预测的自下而上方法的一部分
- 作者：Otsubo Yuki;Nishijo Taku;Miyazawa Masaaki;Saito Kazutoshi;Mizumachi Hideyuki;Sakaguchi Hitoshi
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Skin sensitization;
- KeratinoSens (TM);
- h-CLAT;
- Hazard identification;
- Bottom-up approach;
89.Lessons learned from read-across case studies for repeated-dose toxicity

机译：从读取的案例研究中学到的重复剂量毒性的经验教训
- 作者：Schultz Terry W.;Cronin Mark T. D.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Read-across;
- Similarity;
- Uncertainty;
- Case studies;
- Repeated-dose toxicity;
- Regulatory acceptance;
90.CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information

机译：CSAHI研究-2：使用人IPS细胞衍生心肌细胞预测药物诱导的预测药物诱导的预测性的多电极阵列系统（MEA60 / 2100）：评估参考化合物和与非临床研究和临床信息的比较
- 作者：Nozaki Yumiko;Honda Yayoi;Watanabe Hitoshi;Saiki Shota;Koyabu Kiyotaka;Itoh Tetsuji;Nagasawa Chiho;Nakamori Chiaki;Nakayama Chiaki;Iwasaki Hiroshi;Suzuki Shinobu;Tanaka Kohji;Takahashi Etsushi;Miyamoto Kaori;Morimura Kaoru;Yamanishi Atsuhiro;Endo Hiroko;Shinozaki Junko;Nogawa Hisashi;Shinozawa Tadahiro;Saito Fumiyo;Kunimatsu Takeshi
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- CSAHi;
- CiPA;
- hiPS-CMs;
- FPD;
- TdP;
- QT prolongation;
- EAD or TA;
- Arrest;
91.Nonclinical pharmacology and toxicology of the first biosimilar insulin glargine drug product (BASAGLAR (R)/ABASAGLAR (R)) approved in the European Union

机译：欧盟批准的第一生物蛋白胰岛素狼生药物产品（Basaglar（R）/ Abasaglar（R））的非临床药理和毒理学
- 作者：Byrd Richard A.;Owens Rebecca A.;Blackbourne Jamie L.;Coutant David E.;Farmen Mark W.;Michael M. Dodson;Moyers Julie S.;Schultze A. Eric;Sievert Michael K.;Tripathi Niraj K.;Vahle John L.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Biosimilar insulin;
- Glucodynamics;
- Insulin glargine;
- Nonclinical;
- Pharmacokinetics;
- Pharmacology;
- Preclinical;
- Rats;
- Toxicology;
92.Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4-dioxane

机译：更新：口服暴露于1,4-二恶烷诱导的肝肿瘤的作用方式（MOA）
- 作者：Dourson Michael L.;Higginbotham Jeri;Crum Jeff;Burleigh-Flayer Heather;Nance Patricia;Forsberg Norman D.;Lafranconi Mark;Reichard John
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Dioxane;
- Regenerative hyperplasia;
- Liver toxicity;
- Mode of action;
- Risk assessment;
93.Evaluation of toxicity studies of flavonoid fraction of Lithocarpus polystachyus Rehd in rodents

机译：啮齿动物岩溶岩岩岩岩岩浆零件毒性研究评价
- 作者：Liang Jian;Chen Shu-xian;Huang Song;Wu Ya-yun;Zhou Cai-Jie;Jiang Dong-xu;Liang Chu-yan;Yuan Hui-qi;Hou Shao-zhen;Lai Xiao-ping
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Lithocarpus polystachyus Rehd;
- Acute toxicity;
- Sub-chronic toxicity;
- Blood analysis;
- Histopathology;
94.Probabilistic derivation of the interspecies assessment factor for skin sensitization

机译：皮肤敏化分析评估因子的概率衍生
- 作者：Bil W.;Schuur A. G.;Ezendam J.;Bokkers B. G. H.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
95.Assessment of environmental risks to groundwater ecosystems related to use of veterinary medicinal products

机译：评估与使用兽医药品相关的地下水生态系统的环境风险
- 作者：Kolar Boris;Finizio Antonio
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Groundwater ecosystem;
- Veterinary medicines;
- Risk assessment;
- Stygofauna;
96.A comprehensive study on in vitro and in vivo toxicological evaluation of Artemisia capillaris

机译：艺术毛细血管毛细血管体外与体内毒理学评价的综合研究
- 作者：Yun Jun-Won;Kim Seung-Hyun;Kim Yun-Soon;You Ji-Ran;Cho Eun-Young;Yoon Jung-Hee;Kwon Euna;Ahn Jae Hun;Jang Ja-June;Che Jeong-Hwan;Kang Byeong-Cheol
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- Artemisia capillaris;
- Traditional medicine;
- Toxicity;
- Subchronic;
- Genotoxicity;
97.Lead substances selection using GHS approach for the classification of mixtures: Case study of painting in the work environment

机译：使用GHS方法选择混合物分类的铅物质选择：在工作环境中绘画的案例研究
- 作者：Kaneko Kazuhiro;Ishii Satoko;Hosohara Sachio;Hirata Tsuyoshi;Masuda Motoshi;Murasawa Kaori;Yamada Airi;Tadokoro Takaaki;Hanzawa Masahiko
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- GHS-based approach;
- Global product strategy;
- Chemical mixture;
- Lead substance;
- Risk assessment;
- Acrylic urethane paint;
- ECETOC TRA;
98.Airborne Asbestos Exposures Associated with Gasket and Packing Replacement: A Simulation Study of Flange and Valve Repair Work and an Assessment of Exposure Variables (vol 71, pg 35, 2014)

机译：与垫圈和包装替换相关的机载石棉曝光：法兰和阀门修理工作的仿真研究以及暴露变量评估（Vol 71，PG 35,2014）
- 作者：Madl Amy K.;Devlin Kathryn D.;Perez Angela L.;Hollins Dana M.;Cowan Dallas M.;Scott Paul K.;White Katherine;Cheng Thales J.;Henshaw John L.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
99.An in vitro approach for comparative interspecies metabolism of agrochemicals

机译：农业化学物质代谢的体外方法
- 作者：Whalley Paul M.;Bartels Michael;Bentley Karin S.;Corvaro Marco;Funk Dorothee;Himmelstein Matthew W.;Neumann Birgit;Strupp Christian;Zhang Fagen;Mehta Jyotigna
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期
- In vitro;
- Comparative;
- Interspecies;
- Metabolism;
- Agrochemicals;
- Pesticide;
- Human;
- Safety;
- Toxicology;
100.Classification schemes for carcinogenicity based on hazard identification serve science and society

机译：基于危险识别服务的致癌性的分类方案 - 科学与社会
- 作者：Loomis Dana;Guyton Kathryn Z.;Straif Kurt;Wild Christopher P.
- 期刊名称：《Regulatory Toxicology and Pharmacology: RTP》 | 2017年第2017期

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有出版物经营许可证

客服微信
服务号