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COMPOSITION COMPRISING ARTEMISIA ANNUA ESSENTIAL OIL HAVING SKIN REGENERATION AND ANTI-OBESITY

机译:包含蒿蒿精油的成分具有皮肤再生和抗肥胖作用

摘要

The present invention relates to a composition comprising an essential oil extracted from Artemisia annua, which has skin-regenerative, antioxidant and anti-obesity effects. The essential oil extracted from Artemisia annua induces the proliferation of epidermal keratinocytes and the synthesis and secretion of type I and type IV collagens of epidermal keratinocytes. The essential oil of the present invention regulates the proliferation of cells by inducing phosphorylation of serine/threonine kinase (AKT) and extracellular signal-regulated kinase (ERK1/2), and thus has an excellent effect on skin regeneration. Also, the essential oil of the present invention has ABTS radical or DPPH radical scavenging activity, and thus shows an excellent antioxidant effect. Further, the essential oil of the present invention has an inhibitory effect on the differentiation of adipocytes, and thus has an excellent anti-obesity effect.
机译:本发明涉及包含提取自青蒿的精油的组合物,其具有皮肤再生,抗氧化剂和抗肥胖作用。从青蒿中提取的精油诱导表皮角质形成细胞的增殖以及表皮角质形成细胞的I型和IV型胶原蛋白的合成和分泌。本发明的精油通过诱导丝氨酸/苏氨酸激酶(AKT)和细胞外信号调节激酶(ERK1 / 2)的磷酸化来调节细胞的增殖,因此对皮肤再生具有优异的作用。另外,本发明的香精油具有ABTS自由基或DPPH自由基清除活性,因此显示出优异的抗氧化作用。此外,本发明的精油对脂肪细胞的分化具有抑制作用,因此具有优异的抗肥胖作用。

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