Streptococcus suis ST3 2- 5- 2-deoxyribose 5-phosphate aldolase mutant from Streptococcus suis ST3

摘要

More particularly, the present invention relates to a mutant of 2-deoxyribose 5-phosphate aldolase derived from Streptococcus suis ST3 strain and a mutant of 2-deoxyribose 5-phosphate aldolase derived from Streptococcus suis ST3 strain, A method for producing a 2-deoxyribose 5-phosphate aldolase mutant, which comprises culturing a gene encoding a deoxyribose 5-phosphate aldolase mutant, a recombinant microorganism into which the gene is introduced, and the recombinant microorganism will be. The 2-deoxyribose 5-phosphate aldolase mutant according to the present invention is low in substrate inhibition against acetaldehyde and excellent in activity, and is useful for the production of lactol containing an antiviral nucleoside, an anticancer agent and a statin-based hyperlipemia therapeutic agent.