Prevention and Treatment of Chinese Herbal Preparation Yinqiaotiangan against Pathologic Model of Streptococcus suis Serotype II in Kunming Mice

摘要

[Objective] This study aimed to investigate the antimicrobial effect of Chinese herbal preparation Yinqiaotiangan against Streptococcus suis serotype II in vivo.[Method] The prevention and treatment tests were conducted with Kunming mice weighing about 18-22 g. In the prevention test,Kunming mice were inoculated with Streptococcus suis serotype II and simultaneously taken orally 0.5,1.0 and 2.0 g/ml Chinese herbal preparation Yinqiaotiangan respectively for continuous 3 d,once a day; the incidence rate,mortality rate and protective rate were detected after 7 d. In the treatment test,Kunming mice were inoculated with Streptococcus suis serotype II to establish the Streptococcus suis serotype II pathogenic model,and then taken orally 0.5,1.0 and 2.0g / ml Chinese herbal preparation Yinqiaotiangan respectively for continuous 3d,twice a day; the mortality rate,cure rate and effective rate were detected after 7d.[Result] Results of the prevention test showed that the protective rate in experimental groups was extremely significantly higher than that in control group ( P0.05) .[Conclusion] The pathologic model of Streptococcus suis serotype II could be effectively prevented and treated by oral intake of low dose of Chinese herbal preparation Yinqiaotiangan in Kunming mice.