METHOD FOR CLINICAL ASSESSMENT OF PROBABILITY NON-MASSIVE PULMONARY ARTERY THROMBOEMBOLIA IN PATIENTS RECEIVING MENOPAUSAL HORMONE THERAPY

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine and can be used for clinical assessment of probability of developing non-massive pulmonary artery thromboembolia (PATE) in patients, receiving menopausal hormone therapy. Clinical signs are determined and following signs are assessed in points: existence of receiving menopausal hormonal therapy agents, appearance on ECG signs of pulmonary heart, presence in Doppler echocardiography signs of right ventricular dysfunction detection in x-ray image of chest signs of pulmonary heart, presence of congenital or acquired disorders hemostasis, from laboratory indicators, such as homocysteine, presence of blood markers of APL syndrome, product of dehydration of fibrin D-dimer above 500 ng/ml, change on side of coagulation system (coagulation and/or platelet haemostasis), occurrence of signs of chronic venous insufficiency for period of using menopausal hormonal therapy, presence of metabolic syndrome, absence of any of following clinical signs is evaluated as 0 points. Obtained points are summed up. If total score is more than 19 a high probability of developing non-massive PATE is determined. If total score ranges from 13 to 18 - moderate probability of developing PATE. If total score is less than 12 - low clinical probability of non-massive PATE.;EFFECT: method improves accuracy and information value of detection of non-massive PATE in females, receiving menopausal hormonal therapy.;1 cl, 2 tbl