首页> 外国专利> Treatment of ‘C terminus of HSP7O-interacting protein’ (CHIP) related diseases by inhibition of natural antisense transcript to CHIP

Treatment of ‘C terminus of HSP7O-interacting protein’ (CHIP) related diseases by inhibition of natural antisense transcript to CHIP

机译:通过抑制CHIP的天然反义转录本来治疗“ HSP7O相互作用蛋白的C末端”(CHIP)相关疾病

摘要

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of ‘C terminus of HSP70-Interacting Protein’ (CHIP), in particular, by targeting natural antisense polynucleotides of ‘C terminus of HSP70-Interacting Protein’ (CHIP). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of CHIP.
机译:本发明涉及反义寡核苷酸,其特别是通过靶向'HSP70相互作用蛋白C末端的天然反义多核苷酸'来调节'HSP70相互作用蛋白C末端'的表达和/或功能。 )。本发明还涉及这些反义寡核苷酸的鉴定及其在治疗与CHIP表达有关的疾病和病症中的用途。

著录项

  • 公开/公告号US9725756B2

    专利类型

  • 公开/公告日2017-08-08

    原文格式PDF

  • 申请/专利权人 CURNA INC.;

    申请/专利号US201414297010

  • 申请日2014-06-05

  • 分类号C12N15/11;C12Q1/68;A61K31/7088;C12N15/113;

  • 国家 US

  • 入库时间 2022-08-21 13:42:47

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