process for producing cells that are capable of converting arabinose.

摘要

process for producing cells that are capable of converting arabinose. The invention relates to a process for producing cells which are capable of converting arabinose, comprising the following steps: a) introduction into a host strain which cannot convert arabinose of the araa, arab and arad genes, such cell is designated as a built cell; b) subnitting the constructed cell to adaptive evolution until an arabinose converting cell is obtained; c) optionally submitting the first arabinose conversion cell to adaptive evolution to improve arabinose conversion; the cell produced in step b) or c) is designated as the first arabinose conversion cell; d) analysis of the complete genome or part of the genome of the first arabinose conversion cell and that of the constructed cell; e) identification of single nucleotide polymorphism (snp's) in the first arabinose conversion cell; and f) use of snp's information in the design of a cell capable of converting arabinose; g) construction of the cell capable of converting arabinose drawn in step f).