PRION PROTEIN AS A RECEPTOR FOR AMYLOID-BETA OLIGOMERS

摘要

The invention provides methods of inhbiting suppression of long termpotentiation, improving acute memoryre-tention and spatial memory performance and treating Alzheimer's disease byadministration of a PrPc antagonist or combinationsthereof. Additionally, this invention provides pharmaceutical kits comprising,and methods for making and using, suchcombinit-tions, as well as methods of identifying molecules that couldfunction as PrP c antagonists.