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Prion Protein as a Receptor for Amyloid-Beta Oligomers
Prion Protein as a Receptor for Amyloid-Beta Oligomers
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机译:on病毒蛋白作为淀粉样β低聚物的受体。
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摘要
The invention provides methods of inhibiting suppression of long term potentiation, improving acute memory retention and spatial memory performance and treating Alzheimer's disease by administration of a PrPc antagonist or combinations thereof. Additionally, this invention provides pharmaceutical kits comprising, and methods for making and using, such combinations, as well as methods of identifying molecules that could function as PrPc antagonists.
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机译:本发明提供了通过施用PrP Sc拮抗剂或其组合来抑制长期增强的抑制,改善急性记忆保持和空间记忆性能以及治疗阿尔茨海默氏病的方法。另外,本发明提供了包括这种组合的药物试剂盒,以及制备和使用这种组合的方法,以及鉴定可用作PrP c Sup>拮抗剂的分子的方法。
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