Disclosed are a source drive circuit, a source drive device, a display panel and a display device, which fall within the technical field of displays, and can solve the problems of high power consumption and short service life of an existing source drive circuit. The source drive circuit comprises a first operational amplifier (OP1) and an output selection unit (MUX), wherein an in-phase input end of the first operational amplifier (OP1) receives an analogue data voltage signal, an anti-phase input end thereof is connected to an output end thereof, and the output end thereof is also connected to a data voltage signal input end of the output selection unit (MUX), so as to amplify the analogue data voltage signal; and the output selection unit (MUX) is also provided with a reference voltage signal input end and a selection control signal input end, and is used to selectively output the amplified analogue data voltage signal or a reference voltage signal (Vref) input via the reference voltage signal input end to a data line under the control of a selection control signal (SEL) input via the selection control signal input end.
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