RNA TRIPLE HELIX STRUCTURES, COMPOSITIONS, AND METHODS

摘要

Provided herein are RNA triple helix structures. The RNA triple helix may be associated with a dendrimer to form an RNA triple helix-dendrimer conjugate, which may be applied to a biological tissue, such as a tumor. The RNA triple helix-dendrimer conjugate may be disposed in a hydrogel. The hydrogel may be applied to a biological tissue, such as a tumor. The hydrogel and/or dendrimer may control the release of the RNA triple helix. Methods of treating a biological tissue and kits also are provided.