/ ALK+ METHOD OF TREATING RESISTANT NON-HODGKIN LYMPHOMA MEDULLOBLASTOMA AND/OR ALK+ NON-SMALL CELL LUNG CANCER USING THIENOTRIAZOLODIAZEPINE COMPOUNDS

摘要

The amorphous thienotriazoloidazepine compound represented by the formula (1) wherein R ¹ is alkyl having ¹ to 4 carbon atoms, R ² is a hydrogen atom, a halogen atom, or a substituted or unsubstituted alkyl group optionally substituted with a halogen atom or a hydroxyl group, R ⁴ is a halogen atom, a halogen atom, an alkyl having 1 to 4 carbon atoms, an alkoxy having 1 to 4 carbon atoms or a cyano, -NR ⁵ - (CH ₂ ) _m R ⁶ R ⁵ is a hydrogen atom or alkyl having 1-4 carbon atoms, m is an integer from 0-4, and R ⁶ is phenyl or pyridyl optionally substituted with halogen atoms) Non-Hodgkin's lymphoma, / RTI and / or ALK + non-small cell lung cancer.