A method of treating resistant non Hodgkin lymphoma medulloblastoma and/or ALK+ non small cell lung cancer in a mammal by administering ajsolid dispersion comprising an amorphous thienotriazolodiazepine compound of the Formula (1) wherein R is alkyl having a carbon number of 1 4 R2 is a hydrogen atom; a halogen atom; or alkyl having a carbon number of 1 4 optionally substituted by a halogen atom or a hydroxyl group R3 is a halogen atom; phenyl optionally substituted by a halogen atom alkyl having a carbon number of 1 4 alkoxy having a carbon number of 1 4 or cyano; NR 5 {CH 2)m R6 wherein R5 is a hydrogen atom or alkyl having a carbon number of 1 4 m is an integer of 0 4 and R6 is phenyl or pyridyl optionally substituted by a halogen atom.
展开▼
机译：一种通过在哺乳动物中施用包含式（1）的无定形硫杂氮杂氮杂二氮杂卓化合物的固体分散体来治疗哺乳动物中的耐药性非霍奇金淋巴瘤，髓母细胞瘤和/或ALK +非小细胞肺癌的方法，其中R是碳数为1 4的烷基。氢原子卤素原子;碳数为1 4的可被卤素原子或羟基取代的烷基R3为卤素原子;或任选地被碳原子数为1 4的碳原子数为1 4的烷氧基的卤素原子烷基或氰基取代的苯基; NR 5（CH 2）m R 6，其中R 5是氢原子或碳原子数为1 4 m的烷基是0 4的整数，R 6是任选地被卤素原子取代的苯基或吡啶基。
展开▼
