The present invention provides a monoclonal antibody specifically binding to an anti-oxidant, particularly a lipoarabinomanan of Mycobacterium tuberculosis, and a use thereof. (A) a light chain variable region containing heavy chain CDR1 to CDR3 of (a) to (c) below and a light chain variable region containing light chain CDR1 to CDR3 of (d) to (f) (B) a heavy chain CDR2 consisting of an amino acid sequence shown by SEQ ID NO: 2; (c) a heavy chain CDR2 consisting of an amino acid sequence represented by SEQ ID NO: 3; (D) light chain CDR1 comprising the amino acid sequence represented by SEQ ID NO: 4, (e) light chain CDR2 comprising the amino acid sequence represented by SEQ ID NO: 5, (f) amino acid sequence represented by SEQ ID NO: 6 Gt; CDR3 / RTI
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机译:本发明提供了与抗氧化剂特别是结核分枝杆菌的脂arabinomanan特异性结合的单克隆抗体及其用途。 (A)包含下面(a)至(c)的重链CDR1至CDR3的轻链可变区和包含(d)至(f)的轻链CDR1至CDR3的轻链可变区(B)重链CDR2由SEQ ID NO:2所示的氨基酸序列组成; (c)由SEQ ID NO:3表示的氨基酸序列组成的重链CDR2; (D)轻链CDR1,其包含SEQ ID NO:4所示的氨基酸序列;(e)轻链CDR2,其包含SEQ ID NO:5所示的氨基酸序列,(f)SEQ ID NO:5所示的氨基酸序列: 6吨; CDR3 RTI>
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