首页> 外国专利> 2 SI-1309 Lactobacillus fermentum strain SI-1309 isolated from pickled fish having toll-like receptor 2-mediated immune activity and antimicrobial activity against pathogen and use thereof

2 SI-1309 Lactobacillus fermentum strain SI-1309 isolated from pickled fish having toll-like receptor 2-mediated immune activity and antimicrobial activity against pathogen and use thereof

机译：从具有收费型受体2介导的对病原体的免疫活性和抗菌活性的腌制鱼中分离的2株SI-1309发酵乳杆菌菌株SI-1309及其用途

页面导航

摘要
著录项
相似文献

摘要

The present invention relates to a Lactobacillus fermentum SI-1309 strain derived from salted and fermented fish having antimicrobial activity against pathogenic bacteria, and more particularly to a method for producing Lactobacillus sp. Lactobacillusfermentum SI-1309 isolates were identified and genetically identified. In addition, the expression of the tole-like receptor 2 was increased by the strain, and the immune activity was increased through the increase of the receptor. Thus, it was confirmed that the strain exhibited an antimicrobial activity inhibiting the growth of pathogenic bacteria. Therefore, it can be very usefully used for immuno-enhancing and antibacterial compositions using the present invention.

机译：发酵乳杆菌SI-1309菌株技术领域本发明涉及衍生自对病原菌具有抗菌活性的盐腌和发酵鱼的发酵乳杆菌SI-1309菌株，更具体地，涉及生产乳杆菌sp的方法。鉴定了乳杆菌发酵 SI-1309并进行了遗传鉴定。另外，通过该菌株增加了环状抗体2的表达，并且通过增加了受体的免疫活性。因此，证实了该菌株表现出抑制病原细菌生长的抗微生物活性。因此，它可以非常有用地用于使用本发明的免疫增强和抗菌组合物。 展开▼

著录项

公开/公告号KR101746047B1

专利类型

公开/公告日2017-06-12

原文格式PDF

申请/专利权人 농업회사법인 선일바이오 주식회사;
展开▼

申请/专利号KR20150122716

发明设计人 조경현;최성민;우미희;방미선;이희연;
展开▼

申请日2015-08-31

分类号C12N1/20;A23K10/16;A23L33/135;A61K35/742;C12R1/225;

国家 KR

入库时间 2022-08-21 13:25:20

相似文献

专利

外文文献

1. 真菌次生代谢产物中具有抗菌活性化合物的分离制备及用途 [P] . 中国专利： CN109593074B . 2020.07.28

2. 真菌次生代谢产物中具有抗菌活性化合物的分离制备及用途 [P] . 中国专利： CN109593074A . 2019-04-09

3. 2 SI-1309 Lactobacillus fermentum strain SI-1309 isolated from pickled fish having toll-like receptor 2-mediated immune activity and antimicrobial activity against pathogen and use thereof [P] . 韩国专利： KR20170025773A . 2017-03-08

机译：从具有收费型受体2介导的对病原体的免疫活性和抗菌活性的腌制鱼中分离的2株SI-1309发酵乳杆菌菌株SI-1309及其用途

4. HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME [P] . US2021322493A1 . 2021-10-21

机译：具有抗肥胖活性的人源性乳杆菌Mg4231或乳杆菌发酵乳杆菌Mg4244菌株，以及包含该抗肥胖活性的组合物

5. HUMAN BODY-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY AND COMPOSITION COMPRISING SAME [P] . 世界知识产权组织专利： WO2020045972A1 . 2020-03-05

机译：人源发酵乳杆菌MG4231或发酵乳杆菌MG4244具有抗肥胖活性和组成相同的菌株

1. Evaluation of the Antimicrobial Activity of Endophytic Fungus Isolated from Cocos nucifera(L.) Cotyledon against Medically-Important Pathogens [J] . Byran N. Fuego, Kyla G. Romano, Charlmaine D. Pinlac, 生物科学与医学（英文） . 2021,第001期

2. Innate Cytokine Responses and Toll-Like Receptor Induced by Recombinant Porcine Rotavirus VP6 and VP7 Proteins Expressing in Lactobacillus plantarumNC8 Strain Colonization in Mice [J] . Seria Masole Shonyela, Wentao Yang, Guilian Yang, 疫苗（英文） . 2020,第001期

3. Influence of pH, Heat and Enzymatic Treatments on the Activity of Antibacterial Substance in MRS and Milk Media Produced by Lactobacillus fermentum F6 [J] . ZHANG Yong, LIU Yong, BAO Yan, 中国农业科学：英文版 . 2010,第006期

4. Influence of pH, Heat and Enzymatic Treatments on the Activity of Antibacterial Substance in MRS and Milk Media Produced by Lactobacillus fermentum F6 [J] . ZHANG Yong, LIU Yong, BAO Yan, 农业科学学报（英文版） . 2010,第006期

5. Adjuvant activity of Pasteurella multocida A strain, Pasteurella multocida B strain and Salmonella typhimurium bacterial DNA on cellular and humoral immunity responses against Pasteurella multocida specific strain infections in Balb/c mice [J] . Maryam Homayoon, Yahya Tahamtan, Mohammad Kargar, 亚太热带医药杂志（英文版） . 2018,第005期

6. In vitro immunomodulatory activity of Lactobacillus fermentum CECT5716 and Lactobacillus salivarius CECT5713: two probiotic strains isolated from human breast milk. [J] . Perez Cano FJ, Dong H, Yaqoob P Immunobiology: Zeitschrift fur Immunitatsforschung . 2010,第12期

7. In vitro immunomodulatory activity of two probiotic strains isolated from human breast milk: Lactobacillus salivarius CECT5713 and Lactobacillus fermentum CECT5716 [J] . F. J. Pérez-Cano, P. Yaqoob Proceedings of the Nutrition Society . 2010,第OCE3期

8. Evidence for chromosomal determination of fungicidal activity in strains of Lactobacillus brevis and Lactobacillus fermentum isolated from fermented foods [J] . Osuntoki AA, Gbenle GO, Olukoya DK Folia microbiologica . 2003,第1期

9. Antimicrobial activity characteristic on Cell-free broth of potential Lactobacillus brevis P-319 isolated from sauerkraut [C] . Li Yue, Sun Yumei, Xiaohong Xu, 2011 International Conference on Remote Sensing, Environment and Transportation Engineering . 2011

10. Dectin-1 and toll-like receptor 2: Recognition of pathogens through multiple receptors shapes the innate immune response. [D] . Gantner, Benjamin N. 2004

11. Antibacterial and Antioxidant Activities of Acid and Bile Resistant Strains of Lactobacillus fermentum Isolated from Miang [O] . Srikanjana Klayraung, Siriporn Okonogi 2009

12. Six practical diets were formulated to contain 2.6 (the basal diet), 48.9, 95.5, 189.83, 382.4, 779.53 mg/kg vitamin C diet. After 8 weeks of feeding, growth performance, antioxidant status, and innate immunity of juvenile pufferfish were analyzed. Results showed that specific growth rate and protein efficiency ratio in fish fed diets supplemented with vitamin C were significantly higher than in fish fed the control diet. Dietary vitamin C significantly up-regulated the expression levels of growth hormone receptors and Insulin-like growth factor. Blood cell numbers and respiratory burst activity were enhanced in fish fed vitamin C diet. Serum alkaline phosphatase, glutamic-pyruvic transaminase, and glutamic-oxaloacetic transaminase activity were significantly influenced by the dietary vitamin C levels. Fish fed diets supplemented with vitamin C showed increased hepatic superoxide dismutase, glutathione peroxidase, and catalase activity, but decreased malondialdehyde activity. In addition, we found that dietary vitamin C can significantly up-regulate the expression levels of immune-related genes (HSP70, HSP90, BAFF, TNF-α and IL-6) in liver. These results indicate that dietary vitamin C can significantly influence growth performance, antioxidant status, and innate immunity of pufferfish. [O] . Cheng C-H, Liang H-Y., Guo Z-X., 2017