首页> 外国专利> HUMAN BODY-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY AND COMPOSITION COMPRISING SAME

HUMAN BODY-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY AND COMPOSITION COMPRISING SAME

机译:人源发酵乳杆菌MG4231或发酵乳杆菌MG4244具有抗肥胖活性和组成相同的菌株

摘要

The present invention relates to a human body-derived Lactobacillus fermentum MG4231 or Lactobacillus fermentum MG4244 and a pharmaceutical composition, food composition, a quasi-drug composition, and a health functional food, each of which comprises the same as an effective ingredient for preventing or treating obesity-related diseases. The Lactobacillus fermentum MG4231 or Lactobacillus fermentum MG4244 strain of the present invention exhibits the anti-obesity activity of inhibiting the activity of lipase enzymes, the differentiation of preadipocytes, and the accumulation of triglyceride, has an excellent ability to form colonies on epithelial cells of the digestive duct through excellent self-aggregation ability, and is resistant to acid and bile salts, thereby finding various applications in pharmaceutical compositions, food compositions or quasi-drug compositions, and health functional foods for treating and preventing obesity-related diseases.
机译:本发明涉及人源性发酵乳杆菌MG4231或发酵乳杆菌MG4244以及药物组合物,食物组合物,准药物组合物和保健功能性食物,它们各自包含与预防或预防的有效成分相同的物质。治疗肥胖相关疾病。本发明的发酵乳杆菌MG4231或发酵乳杆菌MG4244菌株显示出抑制脂肪酶活性的抗肥胖活性,前脂肪细胞的分化和甘油三酸酯的积累,具有优异的在结肠上皮细胞上形成集落的能力。消化管具有出色的自聚集能力,并且对酸和胆汁盐具有抗性,因此在治疗和预防肥胖症相关疾病的药物组合物,食品组合物或准药物组合物以及保健功能食品中都有各种应用。

著录项

  • 公开/公告号WO2020045972A1

    专利类型

  • 公开/公告日2020-03-05

    原文格式PDF

  • 申请/专利权人 MEDIOGEN;

    申请/专利号WO2019KR10962

  • 发明设计人 PAEK NAM SOO;KANG CHANG HO;

    申请日2019-08-27

  • 分类号C12N1/20;A23L33/135;A61K35/747;A61P3/04;C12R1/225;

  • 国家 WO

  • 入库时间 2022-08-21 11:13:05

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