首页> 外国专利> HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME

HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME

机译:人源发酵乳杆菌MG4231或发酵乳杆菌MG4244具有抗肥胖活性,且其组成相同

摘要

The present invention relates to: human-derived Lactobacillus fermentum MG4231 or Lactobacillus fermentum MG4244; and a pharmaceutical composition, a food composition, a quasi-drug composition and a health functional food for preventing or treating obesity-related diseases, all of which comprise same as an active ingredient. A lactobacillus fermentum MG4231 strain or MG4244 strain of the present invention exhibits an anti-obesity activity for inhibiting a lipase enzyme activity, inhibiting preadipocyte differentiation and inhibiting triglyceride accumulation, has an excellent ability to form colonies on the epithelial cells of a digestive tract by means of an excellent self-aggregation ability, and has resistance to acidity and bile salts, thereby being variously usable as a pharmaceutical composition, a food composition, a quasi-drug composition and a health functional food for the purpose of treating and preventing obesity-related diseases.
机译:本发明涉及人源发酵乳杆菌MG4231或发酵乳杆菌MG4244。用于预防或治疗与肥胖有关的疾病的药物组合物,食品组合物,准药物组合物和保健功能食品均包含与有效成分相同的成分。本发明的发酵乳杆菌MG4231菌株或MG4244菌株显示出抑制脂肪酶活性,抑制脂肪前细胞分化和甘油三酸酯蓄积的抗肥胖活性,具有通过消化道在消化道上皮细胞上形成菌落的优异能力。具有优异的自聚集能力,并且具有耐酸性和胆汁盐的能力,因此可作为治疗和预防肥胖症相关的药物组合物,食品组合物,准药物组合物和保健功能食品而各种使用疾病。

著录项

  • 公开/公告号WO2020045971A1

    专利类型

  • 公开/公告日2020-03-05

    原文格式PDF

  • 申请/专利权人 MEDIOGEN;

    申请/专利号WO2019KR10961

  • 发明设计人 PAEK NAM SOO;KANG CHANG HO;

    申请日2019-08-27

  • 分类号C12N1/20;A23L33/135;A61K35/747;A61P3/04;C12R1/225;

  • 国家 WO

  • 入库时间 2022-08-21 11:13:05

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