首页> 外国专利> HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME

HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME

机译:具有抗肥胖活性的人源性乳杆菌Mg4231或乳杆菌发酵乳杆菌Mg4244菌株,以及包含该抗肥胖活性的组合物

摘要

The present invention relates to: human-derived Lactobacillus fermentum MG4231 or Lactobacillus fermentum MG4244; and a pharmaceutical composition, a food composition, a quasi-drug composition and a health functional food for preventing or treating obesity-related diseases, all of which include the same as an active ingredient. A Lactobacillus fermentum MG4231 strain or MG4244 strain of the present invention exhibits an anti-obesity activity for inhibiting a lipase enzyme activity, inhibiting preadipocyte differentiation and inhibiting triglyceride accumulation, has an excellent ability to form colonies on the epithelial cells of a digestive tract by means of an excellent auto-aggregation ability, and has resistance to acid and bile, thereby being variously usable as a pharmaceutical composition, a food composition, a quasi-drug composition and a health functional food for the purpose of treating and preventing obesity-related diseases.
机译:本发明涉及:人衍生的乳杆菌Mg4231或乳杆菌Fermentum Mg4244; 和药物组合物,食物组合物,准药物组合物和用于预防或治疗肥胖相关疾病的健康功能食品,所有疾病包括与活性成分相同。 本发明的乳酸杆菌发酵Mg4231菌株或Mg4244株表现出用于抑制脂肪酶活性的抗肥胖活性,抑制脂肪酶分化并抑制甘油三酯积累,具有通过手段的消化道上皮细胞形成菌落的优异能力 具有优异的自动聚集能力,并且具有耐酸和胆汁的耐药性,从而各种可用作药物组合物,食品组合物,准药物组合物和健康功能食品,以治疗和预防肥胖有关的疾病 。

著录项

  • 公开/公告号US2021322493A1

    专利类型

  • 公开/公告日2021-10-21

    原文格式PDF

  • 申请/专利权人 MEDIOGEN;

    申请/专利号US201917271076

  • 发明设计人 NAM SOO PAEK;CHANG HO KANG;

    申请日2019-08-27

  • 分类号A61K35/747;A23L33/135;C12N1/20;

  • 国家 US

  • 入库时间 2022-08-24 21:49:39

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