Methods of treating solid tumors and use of biomarkers as predictors of clinical sensitivity to immunomodulatory therapy

摘要

A method of identifying a subject having a solid tumor susceptible to a therapeutic compound, comprising administering the therapeutic compound to a subject having a solid tumor; obtaining a sample from the subject; the level of biomarkers in a sample from the subject Measuring and diagnosing that the subject is likely to respond to the therapeutic compound if the level of the biomarker in the sample of the subject changes relative to the reference level of the biomarker. [Selected figure] Figure 1A