pharmaceutical composition, method of preventive treatment of a hemorrhagic syndrome in a patient with hemophilia a or b and method of treatment of a hemorrhagic accident in a patient with hemophilia a or b

摘要

A pharmaceutical composition, method for the preventive treatment of a hemorrhagic syndrome in a patient with hemophilia a or b and a method of treating a hemorrhagic accident in a patient with hemophilia a or b. The present invention relates to a pharmaceutical composition comprising a fatox xa (modified). (gdxa), said modified gdxa being non-thrombogenic, capable of binding to tfpi, but not capable of binding to phospholipids, to prevent or treat a bleeding accident in a patient with haemophilia a or b or without inhibitor.