Visual Perception and Visuospatial Abilities among Children with Hemophilia: A Mexican Sample who Experienced Cerebral Hemorrhage.

摘要

The goal of this study was to examine the impact of focal brain injury on visual perception and visuospatial abilities outcomes in Mexican children with hemophilia who had intracranial hemorrhage. We assessed ten boys with hemophilia with hemorrhagic stroke (HIC), six boys with hemophilia without hemorrhagic stroke (HH), and ten boys without hemophilia as controls (CTL). Each participant with hemophilia was matched case-by-case with a male control subject without hemophilia chosen from the same classroom, living in the same neighborhood, sharing similar socioeconomic status and age. Each child in the HIC and HH groups underwent a magnetic resonance imaging (MRI) in order to verify evidence of new bleeds or brain injury prior to the neuropsychological assessment. Full Scale (FSIQ) from the Wechsler Intelligence Scale for Children-Mexican Revision and Visual Perception and Visuospatial abilities domains from a neuropsychological assessment battery for Spanish-speaking children were employed for our analysis. The results showed that the HIC group performed in the low average range on the FSIQ, which was significantly worse than the control group (HH). The HIC group showed significantly lower performance on superimposed shapes and blurred figures (HIC < HH) and visuospatial abilities and line orientation (HIC < CTL) than its controls. The present results suggest that it is not the ability to recognize objects that is impaired in the HIC group, but the ability to identify objects under less favorable conditions. Our findings may have therapeutic and rehabilitative implications for the management of children with hemophilia with early focal brain lesions.