VACUUM TUBES FOR BLOOD COLLECTION CONTAINING PROTEASE INHIBITORS TO ASSESS THE ACTIVATION OF A CONTACT SYSTEM

摘要

This paper proposes a vacuum tube for blood sampling, containing a protease inhibitor cocktail in liquid form, and its use to evaluate traits associated with an individual's contact system, including the endogenous level of activation of the contact system, the endogenous level of the drug that targets the contact system component during treatment, and / or the immunogenicity of such a drug.