INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17ALPHA-ACETOXY-11BETHA-4-(N,N-DIMETHYL-AMINO)-PHENYL-19-NORPREGNA-4,9-DIENE-3,20-DIONE AND THE NEW INTERMEDIATES OF THE PROCESS

摘要

A new industrial process for the synthesis of solvate-free 17-acetoxy-11-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB-2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process.