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TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES

机译:在影像和抗肿瘤治疗中常用的具有可调药代动力学的功能性构造

摘要

The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer. The compounds are represented by the following formula: (I) or a pharmaceutically acceptable salt thereof.
机译:本技术提供了用于胶质瘤,乳腺癌,肾上腺皮质癌,子宫颈癌,外阴癌,子宫内膜癌,原发性卵巢癌的成像和/或治疗的化合物以及包括这种化合物的组合物。 ,转移性卵巢癌,非小细胞肺癌,小细胞肺癌,膀胱癌,结肠癌,原发性胃腺癌,原发性大肠腺癌,肾细胞癌和/或前列腺癌。所述化合物由下式表示:(I)或其药学上可接受的盐。

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