METHOD OF MANUFACTURING COMPOSITE BONE IMPLANTS, METHOD OF MANUFACTURING POWDERED RAW MATERIAL FOR SUCH IMPLANTS, SUCH POWDERED RAW MATERIAL AND BONE IMPLANT

摘要

The method of implant production includes a step of preparing a raw material in powdered form and a step of forming of the implant by pressing. In the material preparation stage fragments of the natural silk fibre are cryogenically grinded and mixed with powdered synthetic nanometric hydroxyapatite. The proportion of hydroxyapatite in the powdered raw material is from 70% to 95% by weight. Composite powder, which is the raw material for implant formation, contains hydroxyapatite with a particle size of not more than 80 nm and a molar ratio of calcium to phosphorus in the range from 1.57 to 1.67. The composite bone implant contains fibroin and from 70% to 95% by weight of hydroxyapatite with a particle size of not more than 80 nm, and a molar ratio of calcium to phosphorus from 1.57 to 1.65. The Young's modulus of the implants material is in the range from 7.5 to 9.5 GPa, its total porosity ranges from 10 to 20%. The bending strength of such an implant is at least 30 MPa, and its compression strength is at least 100 MPa.