3 A Method and Kit for simultaneously detecting multiple diseases based on 3D protein nanoparticle probes

摘要

TECHNICAL FIELD The present invention relates to a simultaneous detection method for multiple diseases based on highly sensitive three-dimensional protein nanoparticle probes and a kit for simultaneous detection of multiple diseases using highly sensitive three-dimensional protein nanoparticle probes. More particularly, A conjugation pad in which signal molecules are planted; A membrane comprising a protein nanoparticle probe in which a disease marker-specific epitope is fused and expressed on the surface of a self-assembly protein; And an absorbent pad, and a method for simultaneous detection of multiple diseases using the kit. The protein nanoparticle probe according to the present invention is characterized in that disease marker specific epitopes on the surface have proper orientation and are highly integrated And can detect various disease marker specific epitopes at various ratios by controlling the mixing ratios of these marker markers, and a method of detecting disease markers using the method can detect various disease marker specific epitopes on the surface of protein nanoparticles And is excellent in sensitivity and accuracy.