The invention positron emission tomography as (PET) on the precursor, the production process and application of the radiopharmaceutical for, and more particularly 4 as a precursor, a method of manufacturing the same and a single step by using this, having an organic salt of departure 18 F To a method for producing a desired PET radiopharmaceutical in a high radiochemical yield within a short production time. The precursor comprising the quaternary organic salt leaving group of the present invention can simplify the conventional multi-step complex radioactive pharmaceutical preparation to a single step, can reduce the production cost by eliminating the need for an excessive phase transfer catalyst, And the reaction speed is fast. This feature is suitable for mass production of PET radiopharmaceuticals by automated synthesis systems.
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