首页> 外国专利> MEANS FOR TREATMENT OF DISEASE WITH MACULAR OEDEMA DUE TO EXCESSIVE VEGF-A EXPRESSION

MEANS FOR TREATMENT OF DISEASE WITH MACULAR OEDEMA DUE TO EXCESSIVE VEGF-A EXPRESSION

机译:过度表达VEGF-A可治疗黄斑水肿的疾病

摘要

The invention relates to the field of medicine and can be used in the pharmaceutical industry for producing a drug for treating a disease correlated with macular oedema associated with VEGF-A overexpression. An F(ab)2-fragment of anti-VEGF-A antibody is provided as active substance of the drug for treating a disease correlated with macular oedema caused by VEGF-A overexpression. Moreover, the aforementioned dimer can comprise additional amino acid sequences, which improve the pharmacological properties thereof. The use of the present invention makes it possible to improve the ease of use of the anti-VEGF-A-therapy for macular oedema.
机译:本发明涉及医学领域,可用于制药工业中生产用于治疗与黄斑水肿相关的疾病的药物,所述黄斑水肿与VEGF-A过表达有关。提供抗VEGF-A抗体的F(ab)2片段作为用于治疗与由VEGF-A过表达引起的黄斑水肿相关的疾病的药物的活性物质。此外,上述二聚体可以包含另外的氨基酸序列,其改善了其药理特性。本发明的使用使得可以改善抗-VEGF-A疗法用于黄斑水肿的易用性。

著录项

  • 公开/公告号RU2016148710A3

    专利类型

  • 公开/公告日2018-06-13

    原文格式PDF

  • 申请/专利权人

    申请/专利号RU20160148710

  • 发明设计人

    申请日0000-00-00

  • 分类号A61K39/395;A61P27/02;

  • 国家 RU

  • 入库时间 2022-08-21 12:36:21

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号