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AB6 FAMILY DESIGNER LIGANDS OF TGF-BETA SUPERFAMILY
AB6 FAMILY DESIGNER LIGANDS OF TGF-BETA SUPERFAMILY
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机译:TGF-BETA超家族的AB6家族设计师药物
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摘要
A non-naturally occurring chimeric polypeptide having an activity provided by a TGF-beta family member is disclosed. The chimeric polypeptide of an embodiment comprises two or more domains or fragments from parental TGF-beta proteins operably linked such that the resulting polypeptide is capable of modulating a pathway associated with a TGF-beta family member. In one embodiment, the pathway is a SMAD or DAXX pathway.
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