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Modified glucoamylase enzymes and yeast strains having enhanced bioproduct production

机译：修饰的葡糖淀粉酶和酵母菌株具有增强的生物制品生产能力

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摘要

The invention is directed to non-natural yeast able to secrete significant amounts of glucoamylase into a fermentation media. The glucoamylase can promote degradation of starch material generating glucose for fermentation to a desired bioproduct, such as ethanol. The glucoamylase can be provided in the form of a glucoamylase fusion protein having a S. cerevisiae mating factor alpha 2 (Sc MFα2) or repressible acid phosphatase (Sc PHO5) secretion signal.

机译：本发明涉及能够将大量的葡糖淀粉酶分泌到发酵培养基中的非天然酵母。葡糖淀粉酶可以促进淀粉物质的降解，产生用于发酵的葡萄糖，以发酵成所需的生物产物，例如乙醇。葡糖淀粉酶可以以具有~~的葡糖淀粉酶融合蛋白的形式提供。酿酒酵母伴侣因子2（ScMFα2）或可抑制性酸性磷酸酶（Sc PHO5）分泌信号。~~ ~~展开▼~~

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公开/公告号US10364421B2

专利类型

公开/公告日2019-07-30

原文格式PDF

申请/专利权人 CARGILL INCORPORATED;
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申请/专利号US201615548812

发明设计人 CHRISTOPHER K. MILLER;ANA NEGRETE-RAYMOND;JON VELDHOUSE;AMIT VAS;
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申请日2016-02-05

分类号C12N9/34;C07K14/395;C12N9/16;C12P19/14;

国家 US

入库时间 2022-08-21 12:15:19

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