DRUG AND LAYERED SILICATE COMPOSITE WITH IMPROVED ORAL BIOAVAILABILITY, ORAL PHARMACOLOGICAL COMPOSITION CONTAINING THE COMPOSITE AND METHOD FOR PRODUCING THE COMPOSITE

摘要

A drug and layered silicate composite is provided. The drug and layered silicate contains layered silicate powders; and a drug compound bound to between layers of the silicate powders, wherein the drug compound is present in an amorphous state in the composite. Using such a composite may significantly improve absorption and bioavailability of a sorafenib compound.