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Antibodies and Elisas for Alpha Klotho

机译:Alpha Klotho的抗体和ELISA

摘要

An antibody and/or binding fragment thereof, wherein the antibody and/or binding fragment thereof comprises a light chain variable region and a heavy chain variable region, the light chain variable region comprising complementarity determining region (CDR) CDR-L3 and the heavy chain variable region comprising CDR-H1, CDR-H2 and CDR-H3, with the amino acid sequences of said CDRs comprising one or more of the sequences set forth below: CDR-L3; selected from any one of SEQ ID NOs: 123, 126-130, 142, 148 or 149; CDR-H1: SEQ ID NOs: 121 or 124; CDR-H2; SEQ ID NOs: 122 or 125; and/or CDR-H3: selected from any one of SEQ ID NOs: 196-226.
机译:抗体和/或其结合片段,其中所述抗体和/或其结合片段包含轻链可变区和重链可变区,所述轻链可变区包含互补决定区(CDR)CDR-L3和重链包含CDR-H1,CDR-H2和CDR-H3的可变区,所述CDR的氨基酸序列包含一个或多个以下列出的序列:CDR-L3;和选自SEQ ID NO:123、126-130、142、148或149中的任一个; CDR-H1:SEQ ID NO:121或124; SEQ ID NO:121或124。 CDR-H2; SEQ ID NOs:122或125;和/或CDR-H3:选自SEQ ID NO:196-226中的任何一个。

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