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eye drops, and method for stabilizing an eye drop, having an excellent effect on promoting the cure of a corneal disorder

机译:滴眼剂和稳定滴眼剂的方法,对促进角膜疾病的治愈具有极好的效果

摘要

The aim of the invention is to maximize the efficacy of, minimize the incidence of side effects of, and improve the storage stability of eye drops containing: a peptide (sssr), whose amino acid sequence is represented by ser-ser-arg or its pharmacologically acceptable sa and a peptide (fglm), whose amino acid sequence is represented by phe-gly-leu-met-nh2, or its pharmacologically acceptable salt. the concentration ratio between sssr or its pharmacologically acceptable salt and fglm or its pharmacologically acceptable salt is from 1/15 to 1/50. the concentration of sssr or its pharmacologically acceptable salt is between 0.001% and 0.3% (w / v) and the concentration of fglm or its pharmacologically acceptable salt is between 0.015% and 1.5% (w / v) v). the ph of the eye drops is kept between 2.5 and 6.5.
机译:本发明的目的是最大化滴眼剂的功效,降低其副作用的发生率并改善其储存稳定性,所述滴眼剂包含:一种肽(sssr),其氨基酸序列由ser-ser-arg或其氨基酸代表。药理学上可接受的盐;肽(fglm),其氨基酸序列由phe-gly-leu-met-nh2表示,或其药理学上可接受的盐。 ssssr或其药学上可接受的盐与fglm或其药学上可接受的盐之间的浓度比为1/15至1/50。 sssr或其药理学上可接受的盐的浓度在0.001%至0.3%(w / v)之间,fglm或其药理学上可接受的盐的浓度在0.015%至1.5%(w / v)v之间。滴眼液的酸碱度保持在2.5至6.5之间。

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