compound, pharmaceutical composition, and method for treating disorders associated with glutamatergic signal transmission irregularities and central nervous system disorders.

摘要

Compounds of formula I are provided herein and also pharmaceutically acceptable salts thereof, wherein the substituents are as described in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for treating or preventing mglur5-mediated disorders, such as acute and / or chronic neurological disorders, cognitive disorders and memory deficits, as well as acute and chronic pain.