CXCR4 signaling in central nervous system regeneration: friend or foe?

摘要

The knockout of the chemokine C-X-C motif chemokine receptor 4(CXCR4)in growthstimulated retinal ganglion cells(RGCs)has a multiplicative effect on optic nerve regeneration.C-X-C motif chemokine ligand 12(CXCL12),the exclusive ligand of CXCR4.