首页> 外文期刊>Neurosurgery >Biological restoration of central nervous system architecture and function: part 3-stem cell- and cell-based applications and realities in the biological management of central nervous system disorders: traumatic, vascular, and epilepsy disorders.
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Biological restoration of central nervous system architecture and function: part 3-stem cell- and cell-based applications and realities in the biological management of central nervous system disorders: traumatic, vascular, and epilepsy disorders.

机译:中枢神经系统结构和功能的生物修复:第3部分基于干细胞和细胞的应用和中枢神经系统疾病(创伤,血管和癫痫病)的生物管理中的现实。

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摘要

STEM CELL THERAPY has emerged as a promising novel therapeutic endeavor for traumatic brain injury, spinal cord injury, stroke, and epilepsy in experimental studies. A few preliminary clinical trials have further supported its safety and early efficacy after transplantation into humans. Although not yet clinically available for central nervous system disorders, stem cell technology is expected to evolve into one of the most powerful tools in the biological management of complex central nervous system disorders, many of which currently have limited treatment modalities. The identification of stem cells, discovery of neurogenesis, and application of stem cells to treat central nervous system disorders represent a dramatic evolution and expansion of the neurosurgeon's capabilities into the neurorestoration and neuroregeneration realms. In Part 3 of a 5-part series on stem cells, we discuss the theory, experimental evidence, and clinical data pertaining to the use of stem cells for the treatment of traumatic, vascular, and epileptic disorders.
机译:在实验研究中,干细胞疗法已成为一种有希望的新颖疗法,可用于颅脑外伤,脊髓损伤,中风和癫痫。一些初步的临床试验进一步支持了其在人体中的安全性和早期疗效。尽管尚未在临床上用于中枢神经系统疾病的治疗,但干细胞技术有望发展为复杂中枢神经系统疾病的生物管理中最强大的工具之一,其中许多目前治疗方法有限。干细胞的鉴定,神经发生的发现以及干细胞在治疗中枢神经系统疾病中的应用代表了神经外科医生向神经修复和神经再生领域的能力的急剧演变和扩展。在有关干细胞的5部分系列文章的第3部分中,我们讨论了有关使用干细胞治疗创伤性,血管性和癫痫性疾病的理论,实验证据和临床数据。

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