method and kit for detecting at least one mutation in a plurality of hereditary cancer-related genes, and method for selecting a patient exhibiting cancer symptoms

摘要

This disclosure provides rapid, non-invasive methods to determine whether a patient exhibiting cancer symptoms, or at risk for hereditary cancers such as breast cancer, ovarian cancer, colon cancer, or skin cancer, will benefit from treatment with one or more therapeutic agents. These methods are based on the detection of cancer-related hereditary mutations in small volume dry biological fluid samples that are collected using a volumetric absorbent microsampling device (eg, miter tip). Kits for use in practice of the methods are also provided.